Results 121 to 130 of about 8,560 (166)

Influences of Semaphorin 3A Expression on Clinicopathological Features, Human Papillomavirus Status, and Prognosis in Oropharyngeal Carcinoma. [PDF]

Microorganisms, 2020
Pham HT, Kondo S, Endo K, Wakisaka N, Aoki Y, Nakanishi Y, Kase K, Mizokami H, Kano M, Ueno T, Hatano M, Moriyama-Kita M, Sugimoto H, Yoshizaki T.   +13 more
europepmc   +1 more source

Semmaphorin 3 A causes immune suppression by inducing cytoskeletal paralysis in tumour-specific CD8⁺ T cells. [PDF]

Nat Commun
Barnkob MB, Michaels YS, André V, Macklin PS, Gileadi U, Valvo S, Rei M, Kulicke C, Chen JL, Jain V, Woodcock VK, Colin-York H, Hadjinicolaou AV, Kong Y, Mayya V, Mazet JM, Mead GJ, Bull JA, Rijal P, Pugh CW, Townsend AR, Gérard A, Olsen LR, Fritzsche M, Fulga TA, Dustin ML, Jones EY, Cerundolo V.   +27 more
europepmc   +1 more source

Reduced expression of semaphorin 3A in osteoclasts causes lymphatic expansion in a Gorham-Stout disease (GSD) mouse model. [PDF]

J Zhejiang Univ Sci B
Zhang D, Xu H, Qin C, Cai K, Zhang J, Xia X, Bi J, Zhang L, Xing L, Liang Q, Wang W.   +10 more
europepmc   +1 more source

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The role of Semaphorin 3A in oral diseases

Oral Diseases, 2023
AbstractSemaphorin 3A (SEMA3A), also referred to as H‐Sema III, is a molecule with significant biological importance in regulating physiological and pathological processes. However, its role in oral diseases, particularly its association with inflammatory immunity and alveolar bone remodeling defects, remains poorly understood.
Xinyue Zhang, Zhenqi Yang, Demao Zhang, Mingru Bai   +3 more
openaire   +2 more sources

Osteoprotection by semaphorin 3A

Nature, 2012
The bony skeleton is maintained by local factors that regulate bone-forming osteoblasts and bone-resorbing osteoclasts, in addition to hormonal activity. Osteoprotegerin protects bone by inhibiting osteoclastic bone resorption, but no factor has yet been identified as a local determinant of bone mass that regulates both osteoclasts and osteoblasts ...
Mikihito, Hayashi, Tomoki, Nakashima, Masahiko, Taniguchi, Tatsuhiko, Kodama, Atsushi, Kumanogoh, Hiroshi, Takayanagi   +5 more
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Assessment of semaphorin 3A and semaphorin 7A levels in primary Sjogren's syndrome

Rheumatology International, 2022
Sjogren's syndrome (SS) is a chronic autoimmune connective tissue disease. Varying rates of system involvements may be seen in the course of the disease. Semaphorins has multifunctions in several physiological and pathological processes such as immune system regulation.
Urhan, Emre, Urhan, Ayse Camci, Dogan, Halef Okan, Sahin, Ali   +3 more
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Expression of semaphorin 3A, semaphorin 7A and their receptors in multiple sclerosis lesions

Multiple Sclerosis Journal, 2015
Background: Studies in multiple sclerosis (MS) and in experimental models point to a critical role of semaphorin (sema)3A and sema7A in MS pathogenesis. Objective: The objective of this paper is to characterise the expression of sema3A,
Carmen Espejo, E Martinez-Saez, S Ramon Y Cajal   +2 more
exaly   +3 more sources

Semaphorin 3A: an immunoregulator in systemic sclerosis

Rheumatology International, 2015
Semaphorin 3A (sema3A) plays a regulatory role in immune responses, mainly affecting the activation of regulatory T cells. It has been found to correlate with disease activity in rheumatoid arthritis and systemic lupus erythematosus (SLE). To investigate the expression of sema3A in patients with systemic sclerosis (SSc) compared to healthy controls and
Doron, Rimar, Yuval, Nov, Itzhak, Rosner, Gleb, Slobodin, Michael, Rozenbaum, Katy, Halasz, Tharwat, Haj, Nizar, Jiries, Lisa, Kaly, Nina, Boulman, Zahava, Vadasz   +10 more
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The Role Of Semaphorin 3A In The Skeletal System

Critical Reviews in Eukaryotic Gene Expression, 2015
Semaphorin 3A (Sema3A), characterized by a conserved N-terminal "Sema" domain, was originally described as an axon guidance molecule. Recent research indicates that it performs a critical function in the skeletal system. This review highlights recent advances in understanding of the role of Sema3A in the skeletal system as a regulator of bone ...
Peifu, Tang, Pengbin, Yin, Houchen, Lv, Licheng, Zhang, Lihai, Zhang   +4 more
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Localization of semaphorin 3A in the rat cornea

Experimental Eye Research, 2008
Semaphorin 3A (Sema3A) functions to guide the growth of neurons during development. We investigated the localization of Sema3A in the cornea, one of the most sensitive tissues in the body. Immunoblot analysis and reverse transcription-polymerase chain reaction analysis revealed that Sema3A protein and mRNA are expressed in the normal rat cornea ...
Naoyuki, Morishige, Ji-Ae, Ko, Yang, Liu, Tai-Ichiro, Chikama, Teruo, Nishida   +4 more
openaire   +2 more sources