Results 101 to 110 of about 9,266 (196)
Goal. To assess the expression of neurotrophin, a nerve growth factor, amphiregulin, an epidermal growth factor, semaphorin 3A, a nerve repulsion factor, and PGP9.5 protein, a nerve fiber marker, in the skin of patients suffering from atopic dermatitis ...
V. A. Smolyannikova +3 more
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Semaphorins were initially identified as axon guidance molecules that were widely expressed and involved in divergent functions in various organs, including neuronal development and immunological processes.
Mayu Kyohara +13 more
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In human skeletal muscle, myoblasts represent the main population of myogenic progenitors. We previously showed that, beside their myogenic differentiation capacities, myoblasts also differentiate towards osteogenic and chondrogenic lineages, some ...
Séverine Lecourt +10 more
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Role of calpain-mediated p53 truncation in semaphorin 3A-induced axonal growth regulation
Neurite outgrowth represents a critical stage in the correct development of neuronal circuitries, and is dependent on the complex regulation of actin filament and microtubule dynamics by intrinsic as well as extrinsic signals.
Xiaoning Bi +3 more
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Semaphorin 3A and VEGF promote inflammation in retinopathy
Immunological activity in the CNS is largely dependent on an innate immune response and is present in health and heightened in diseases such as diabetic retinopathy, multiple sclerosis, amyotrophic...
Przemyslaw Sapieha +2 more
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Endothelial cell-derived semaphorin 3A inhibits filopodia formation by blood vascular tip cells.
Vascular endothelial growth factor (VEGF)-A is a well-known major chemoattractant driver of angiogenesis--the formation of new blood vessels from pre-existing ones.
Karaman, Sinem +6 more
core +1 more source
A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists
Semaphorin 3A can inhibit axonal growth and induce neuronal apoptosis following binding to neuropilin-1, with the membrane proximal MAM (meprin, A5, mu) domain in neuropilin-1 playing a key role in the formation of a higher order receptor complex.
Eickholt, B J +11 more
core +1 more source
Dietary sphingolipids such as glucosylceramide (GlcCer) are potential nutritional factors associated with prevention of metabolic syndrome. Our current understanding is that dietary GlcCer is degraded to ceramide and further metabolized to sphingoid ...
Seigo Usuki +5 more
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SEMAPHORIN 3A - A NEW INTRATHYMIC SUPPRESSOR FACTOR
Semaphorins were originally identified as axon guidance factors involved in the development of the neuronal system. However, accumulating evidence indicates that several semaphorins, so-called ‘immune semaphorins’, are also involved in various phases of immune responses.
K V Rutto, E P Kisseleva
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Podocyte Shape Regulation by Semaphorin 3A and MICAL-1 [PDF]
Podocytes are complex epithelial cells with foot processes that are essential for the integrity and function of the kidney glomerular filters. Podocyte foot processes linked by slit diaphragms constitute signaling platforms that tightly regulate the cell shape and the function of the filtration barrier.
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