Results 81 to 90 of about 9,266 (196)
Serum Semaphorin 3A Levels in Patients with Behçet’s Disease with and without Vascular Involvement
Aim: Semaphorin 3A is a molecule with identified effects on vasculopathy, angiogenesis, the nervous system, bone homeostasis, and autoimmunity. Its role has been demonstrated in autoimmune and autoinflammatory diseases.
ERDEN, ABDULSAMET +9 more
core +2 more sources
The Journal of Dermatology, Volume 53, Issue 6, Page 867-879, June 2026.ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji +7 more
wiley +1 more source
Biochemical bone biomarkers in plasma cell dyscrasias
British Journal of Haematology, Volume 208, Issue 6, Page 1909-1923, June 2026.Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador +4 more
wiley +1 more source
Semaphorin 3A Inhibits Inflammation in Chondrocytes under Excessive Mechanical Stress
Mediators of Inflammation, 2018 Background. Excessive mechanical stress causes inflammation and destruction of cartilage and is considered one of the cause of osteoarthritis (OA).
Chikako Sumi +7 more
doaj +1 more source
Brain endothelial cells control fertility through ovarian-steroid-dependent release of semaphorin 3A. [PDF]
PLoS Biology, 2014 Neuropilin-1 (Nrp1) guides the development of the nervous and vascular systems, but its role in the mature brain remains to be explored. Here we report that the expression of the 65 kDa isoform of Sema3A, the ligand of Nrp1, by adult vascular endothelial
Paolo Giacobini +18 more
doaj +1 more source
, 2005 Bone tissue is densely innervated, and there is increasing evidence for a neural control of bone metabolism. Semaphorin-3A is a very important regulator of neuronal targeting in the peripheral nervous system as well as in angiogenesis, and knockout of ...
Malaval, Luc +17 more
core +1 more source
Exploring the Potential of Calebin‐A in Targeting Obesity‐Related Genes and Pathways
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Obesity is a global health crisis affecting millions, associated with metabolic disorders such as type 2 diabetes and cardiovascular disease. Calebin‐A, a bioactive compound derived from Curcuma species, has shown promise in managing obesity and its complications.
Ali Mahmoudi +4 more
wiley +1 more source
Semaphorin 3A serum levels are influenced by haemodialysis: what clinical significance?
, 2015 AIM: Semaphorin 3A urinary levels represent an early, predictive biomarker of acute kidney injury and positively correlate with albumin-to-creatinine ratio and serum creatinine in hypertensive patients with chronic kidney disease. Our purpose has been to
Visconti, Luca +8 more
core +1 more source
Control of human thymocyte migration by Neuropilin-1/Semaphorin-3A mediated interactions. [PDF]
, 2007 It is largely established that molecules first discovered in the nervous system are also found in the immune system. Neuropilin-1 (NP-1) was initially identified to mediate semaphorin-induced chemorepulsion during brain development and is also involved ...
Dardenne, M. +23 more
core +1 more source
Advanced Science, Volume 13, Issue 29, 22 May 2026.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source