A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Epigenetic determinants of reproductive potential augment the predictive ability of the semen analysis. [PDF]
Miller RH +8 more
europepmc +1 more source
ABSTRACT Objective Sleep disturbances have been implicated as a risk factor for developing Alzheimer's disease (AD), but evidence linking plasma AD biomarkers to sleep in cognitively unimpaired individuals remains limited. The present study examined associations between evening, morning, and overnight changes in plasma AD biomarkers and measures of ...
Cornelia Sauter +5 more
wiley +1 more source
The Effects of Military Occupation on Semen Analysis. [PDF]
Gregg RW, Aden JK, Glenn TL.
europepmc +1 more source
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein +7 more
wiley +1 more source
From Test Offer to Urologic Follow-up: Acceptability of Semen Analysis in Male Infertility and Preconception Care. [PDF]
Kojo K, Nakazono A, Oguri T.
europepmc +1 more source
Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa +3 more
wiley +1 more source
Chronic Toxoplasma gondii infection and its influence on semen analysis in rats: controlled experimental animal study. [PDF]
El-Beshbishi SN +5 more
europepmc +1 more source
Sperm quality improvement of cryopreserved boar semen through colloidal centrifugation gradient
Boar semen cryopreservation is limited due to the lower thermal shock resistance of sperm cells. A colloidal centrifugation gradient is an enhancement to cryopreservation that could improve the frozen boar semen quality.
Patricia Cervantes-Acosta +6 more
core +1 more source
Comparative Assessment of Manual Versus Automated Semen Analysis and the Role of Novel Biomarker Calprotectin in Screening for Male Factor Infertility. [PDF]
Ab A +8 more
europepmc +1 more source

