Results 61 to 70 of about 694,450 (308)

A numerical study on active control for tiltrotor whirl flutter stability augmentation [PDF]

open access: yes, 2004
The use of active control to augment whirl flutter stability of tiltrotor aircraft is studied by means of a multibody simulation. The numerical model is based on a 1/5 scale semi-span aeroelastic wind tunnel model of a generic tiltrotor concept and ...
Gourinat, Yves   +4 more
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Variable Dampers to Mitigate Structural Demand to Wind Turbines: The Role of the Monitoring System Features for the Effectiveness of the Control Strategy

open access: yesApplied Sciences, 2020
In the last decade, some researchers and professionals have been engaged in the study of methods and techniques that can build high wind turbines while containing construction costs within the limits of economic convenience.
Nicola Caterino   +3 more
doaj   +1 more source

Robust vehicle suspension system by converting active and passive control of a vehicle to semi-active control ystem analytically [PDF]

open access: yes, 2016
This research article deals with a simplified translational model of an automotive suspension system which is constructed by considering the translation motion of one wheel of a car. Passive Vehicle Suspension System is converted into Semi Active Vehicle
Khan, M. Z.   +3 more
core   +1 more source

Integrated Comfort-Adaptive Cruise and Semi-Active Suspension Control for an Autonomous Vehicle: An LPV Approach

open access: yes, 2021
International audienceThis paper presents an integrated linear parameter-varying (LPV) control approach of an autonomous vehicle with an objective to guarantee driving comfort, consisting of cruise and semi-active suspension control.
Tran, Gia Quoc Bao   +9 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Semi-Active Vibration Controllers for Magnetorheological Fluid-Based Systems via Frequency Shaping

open access: yesActuators
This study introduces novel semi-active vibration controllers for magnetorheological (MR) fluid-based vibration control systems, specifically a band-pass frequency-shaped semi-active control (FSSC) and a narrow-band FSSC.
Young T. Choi   +2 more
doaj   +1 more source

Energy harvesting using semi-active nonlinear control

open access: yes, 2013
This paper presents the application of semi-active control for power harvesting using an electromechanical energy harvester. Two semi-active control strategies are proposed in the form of a time-periodic damper and a nonlinear cubic damper.
Ghandchi Tehrani, M.   +6 more
core  

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