Results 41 to 50 of about 13,989,534 (288)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Energy harvesting using semi-active nonlinear control

open access: yes, 2013
This paper presents the application of semi-active control for power harvesting using an electromechanical energy harvester. Two semi-active control strategies are proposed in the form of a time-periodic damper and a nonlinear cubic damper.
Ghandchi Tehrani, M.   +6 more
core   +1 more source

ANFIS optimized semi-active fuzzy logic controller for magnetorheological dampers

open access: yesOpen Engineering, 2016
In this paper, we report on the development of a neuro-fuzzy controller for magnetorheological dampers using an Adaptive Neuro-Fuzzy Inference System or ANFIS.
César Manuel Braz, Barros Rui Carneiro
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The Effectiveness of Innovative Systems Technologies in Smart Building Structuers

open access: yesCivil and Environmental Engineering
Today's industrial processes use a variety of smart structure systems technologies. Various construction devices can significantly enhance a structure's ability to adapt to environmental changes.
Ahmed Mohammed A.   +2 more
doaj   +1 more source

Semi-active control of crankshaft skyhook based on magnetorheological torsional damper

open access: yesFrontiers in Materials, 2022
The purpose of this study was to solve the problem that the damping of rubber or silicone oil torsional dampers used in crankshafts is not adjustable and cannot effectively control torsional vibration at different resonant frequencies.
Wei He   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Effects of the structural period variations and near field earthquakes on a fuzzy controller performance for the variably baffled tuned liquid damper [PDF]

open access: yesNumerical Methods in Civil Engineering
Structural control as a countermeasure against unwanted structural vibrations is divided into three general categories known as passive, active, and semi-active. Among various structural control devices, the tuned Liquid Damper (TLD) can lend itself well
Mahdi Kiani   +2 more
doaj   +1 more source

Optimal Control of Semi-Active Suspension for Agricultural Tractors Using Linear Quadratic Gaussian Control

open access: yesSensors, 2023
In this study, a semi-active suspension based on a hydro-pneumatic mechanism was designed to minimize the ride vibration using a suspension control algorithm. The performance of the algorithm was critical for controlling the characteristics of the target
Da-Vin Ahn   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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