Results 91 to 100 of about 190,015 (291)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
On the stationary Cahn-Hilliard equation: Interior spike solutions
, 1998 We study solutions of the stationary Cahn-Hilliard equation in a bounded smooth domain which have a spike in the interior. We show that a large class of interior points (the "nondegenerate peak" points) have the following property: there exist such ...
Winter, M, Wei, J
core +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Nonlinear Dynamical Analysis on Four Semi-Active Dynamic Vibration Absorbers with Time Delay
Shock and Vibration, 2013 In this paper four semi-active dynamic vibration absorbers (DVAs) are analytically studied, where the time delay induced by measurement and execution in control procedure is included in the system.
Yongjun Shen, Mehdi Ahmadian
doaj +1 more source
Semi-Analytical Solutions for Contaminant
, 2002 New method to determine semi-analytical solutions of one-dimensional contaminant transport problem with nonlinear sorption is described. This method is based on operator splitting approach where the convective transport is realized exactly and the di ...
Transport With Nonlinear +2 more
core
GBT-based semi-analytical solutions for the plastic bifurcation of thin-walled members
, 2010 This paper presents the development and illustrates the application of semi-analytical solutions for plastic buckling (bifurcation) problems involving perfectly straight and uniformly compressed thin-walled metal members.
Gonçalves, Rodrigo +2 more
core +1 more source
Analytical model for the propagation of small debris objects clouds after fragmentations [PDF]
, 2015 Current debris evolutionary models usually neglect fragments smaller than 10 cm because of the high computational effort they add to the simulation. However, small-debris objects can also be dangerous to operational satellites.
Colombo, Camilla +3 more
core +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Stability of numerical method for semi-linear stochastic pantograph differential equations
Journal of Inequalities and Applications, 2016 As a particular expression of stochastic delay differential equations, stochastic pantograph differential equations have been widely used in nonlinear dynamics, quantum mechanics, and electrodynamics.
Yu Zhang, Longsuo Li
doaj +1 more source