Results 51 to 60 of about 30,982 (286)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Road Performance of Fiber-Reinforced Semi-Flexible Pavement Materials

Zhongwai Gonglu
This paper aimed to investigate the reinforcement effects of basalt fiber, polyester fiber, and lignin fiber on semi-flexible pavement materials and study their applicability in different structural layers.
SUN Xuecong, WANG Hongchang, LIU Song
doaj   +1 more source

Research on the mesoscopic viscoelastic property of semi-flexible pavement mixture based on discrete element simulation

Case Studies in Construction Materials, 2022
Semi-flexible pavement (SFP) mixture is a relatively new pavement material that combines the characteristics of the flexibility of asphalt mixtures and the rigidity of cement concrete.
Dayong Jiang, Dongsheng Wang, Zhenhong Chen, Lulu Fan, Junyan Yi   +4 more
doaj   +1 more source

Exploring haptic interfacing with a mobile robot without visual feedback [PDF]

, 2012
Search and rescue scenarios are often complicated by low or no visibility conditions. The lack of visual feedback hampers orientation and causes significant stress for human rescue workers. The Guardians project [1] pioneered a group of autonomous mobile
Jones, Peter E., Penders, Jacques
core   +1 more source

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

Advanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal, Michael M. Becker, Sarah C. L. Fischer   +2 more
wiley   +1 more source

An Empirical Model for Optimal Highway Durability in Cold Regions [PDF]

, 2016
We develop an empirical tool to estimate optimal highway durability in cold regions. To test the model, we assemble a data set containing all highway construction and maintenance projects in Arizona and Washington State from 1990 to 2014.
Yan, Jia
core  

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Effects of Using Silica Fume and Polycarboxylate-Type Superplasticizer on Physical Properties of Cementitious Grout Mixtures for Semiflexible Pavement Surfacing

The Scientific World Journal, 2014
Semi-flexible pavement surfacing is a composite pavement that utilizes the porous pavement structure of the flexible bituminous pavement, which is subsequently grouted with appropriate cementitious materials.
Suhana Koting, Mohamed Rehan Karim, Hilmi Mahmud, Nuha S. Mashaan, Mohd Rasdan Ibrahim, Herdayati Katman, Nadiah Md Husain   +6 more
doaj   +1 more source

Predicting Atomic Charges in MOFs by Topological Charge Equilibration

Advanced Functional Materials, EarlyView.
An atomic charge prediction method is presented that is able to accurately reproduce ab‐initio‐derived reference charges for a large number of metal–organic frameworks. Based on a topological charge equilibration scheme, static charges that fulfill overall neutrality are quickly generated.
Babak Farhadi Jahromi, Sumukh Shankar Sharadaprasad, Rochus Schmid   +2 more
wiley   +1 more source

Pavement structure mechanics response of flexible on semi-flexible overlay that based on the old cement concrete pavement damage

MATEC Web of Conferences, 2015
The old cement pavement damage status directly affect the design of the paving renovation. Based on the state of the old road investigation, combined with the research data at home and abroad, use the control index that average deflection, deflection ...
Jiang Ruinan, Zhu Baolin, Tian Miaomiao, Cao Yanhua   +3 more
doaj   +1 more source