Results 91 to 100 of about 6,501 (215)

Interstitial renal fibrosis due to multiple cisplatin treatments is ameliorated by semicarbazide-sensitive amine oxidase inhibition

open access: yes, 2016
Elucidation of acute kidney diseases and disorders (AKD), including acute kidney injury (AKI), is important to prevent their progression to chronic kidney disease. Current animal AKI models are often too severe for use in evaluating human AKI. Therefore,
Negishi, Kousuke   +6 more
core   +1 more source

13C High-Resolution Nuclear Magnetic Resonance Studies of Enzyme-Substrate Reactions at Equilibrium. Substrate Strain Studies of Chymotrypsin-N-Acetyltyrosine Semicarbazide Complexes [PDF]

open access: yes, 1974
N-Acetyl-L-tyrosine semicarbazide is hydrolyzed by chymotrypsin (EC 3.4.21.1) to N-acetyl-L-tyrosine and semicarbazide. If a high concentration of semicarbazide is present, the equilibrium for the reaction can be shifted from hydrolysis to synthesis ...
Robillard, George   +5 more
core   +1 more source

Synthesis and reducing power assay of methyl semicarbazone derivatives

open access: yesJournal of Saudi Chemical Society, 2014
In the present study we have designed a new pharmacophore ‘Chalconesemicarbazone’ by pharmacophore hybridization approach of drug design. A series of novel chalconesemicarbazones was synthesized and evaluated for their antioxidant activity by reducing ...
Manmohan Singhal   +2 more
doaj   +1 more source

Plasma semicarbazide-sensitive amine oxidase (SSAO) is an independent prognostic marker for mortality in chronic heart failure

open access: yes, 2000
Aims Experimental evidence has suggested that semicarbazide-sensitive amine oxidase is involved in vascular endothelial damage and in the process of atherosclerosis, through the formation of reactive aldehydes, hydrogen peroxide and ammonia from ...
De Kam, PJ   +3 more
core   +1 more source

Synthesis of new urea and semicarbazide derivatives of primaquine [PDF]

open access: yes, 2015
oai:repozitorij.pharma.unizg.hr:pharma_197Primakin je poznati antimalarik i polazni spoj u dizajniranju mnogih potencijalno biološko aktivnih spojeva.
Ubrekić, Tomislav
core  

Scientific Opinion on nitrofurans and their metabolites in food

open access: yesEFSA Journal, 2015
Nitrofurans are antimicrobial agents not authorised for use in food‐producing animals in the European Union. Nitrofurans are rapidly metabolised, occurring in animal tissues as protein‐bound metabolites.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj   +1 more source

Absence of tissue-bound semicarbazide-sensitive amine oxidase activity in carp tissues

open access: yes, 2007
We have previously reported that carp (Cyprinus carpio) tissue mitochondria contain a novel form of monoamine oxidase (MAO), which belongs neither to MAO-A nor to MAO-B of the mammalian enzyme.
Takahashi, Kazuya   +5 more
core   +1 more source

Synthesis and in Vitro Antimicrobial Activity of Some Pyrazolyl-1-carboxamide Derivatives

open access: yesMolecules, 2011
A series of 3,5-disubstituted pyrazole-1-carboxamides were obtained by treatment of chalcones with semicarbazide hydrochloride in dioxane containing sodium acetate/acetic acid as a buffer solution.
Essam Mohamed Sharshira   +1 more
doaj   +1 more source

Inhibition of semicarbazide-sensitive amine oxidase (SSAO) by various antidepressants drugs in monkey platelets

open access: yes, 2016
I examined whether two or more distinct amine oxidases exist in monkey platelets. Km values of amine oxidase in monkey platelets were determined with benzylamine as substrate from the Lineweaver-Burk double reciprocal plots.
OBATA, Toshio
core  

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