Results 81 to 90 of about 6,501 (215)

Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing

Glia, Volume 73, Issue 11, Page 2253-2272, November 2025.
Main Points Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production.
Sarah Geller, Nadège Zanou, Sylviane Lagarrigue, Tamara Zehnder, Cathy Gouelle, Tania Santoro, Cendrine Repond, Paola Bezzi, Francesca Amati, Anne‐Karine Bouzier‐Sore, Ariane Sharif, Luc Pellerin   +11 more
wiley   +1 more source

Batch Synthesis of Primaquine Diphosphate Anti‐Malarial Drug

Chemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.
According to the WHO, a child under the age of five dies every 2 minutes from malaria in Africa. It is therefore paramount that access and availability of anti‐malarial drugs must be improved. We report a process for the synthesis of Primaquine Diphosphate, where key intermediates were obtained in a much shorter reaction time compared to processes ...
Faith M. Akwi, Simthandile Swartbooi, Paul Watts   +2 more
wiley   +1 more source

Effect of Pyridoxamine on Semicarbazide-sensitive Amine Oxidase Activity of Rabbit Lung and Heart

, 1989
Rabbit lung and heart show clorgyline-resistant benzylamine oxidase activity which is sensitive to semicarbazide (SSAO) and α-amino-guanidine. This SSAO activity is inhibited by pyridoxamine with an IC50 of 6·3 × −6 M for lung and of 1·1 × 10−5 M for ...
B Bertocci, L Raimondi, F Buffoni, G Banchelli   +3 more
core   +1 more source

Environmental status and early warning value of the pollutant Semicarbazide in Jincheng and Sishili Bays, Shandong Peninsula, China [PDF]

, 2017
A verified method for measuring Semicarbazide (SEM) in seawater, sediments, and shellfish was developed based on ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
Gong, Xianghong, Xia, Chuanhai, Xu, Yingjiang, Wang, Zhongquan, Tian, Xiuhui, Zhou, Quanli, Ren, Chuanbo, Sun, Chunxiao, Xue, Jinglin, Han, Dianfeng   +9 more
core   +1 more source

Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core

Asian Journal of Organic Chemistry, Volume 14, Issue 10, October 2025.
An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos, Mauro De Nisco, Yoana Pérez‐Badell, Gabriella Pinto, Marco Morelli, Margarita Suárez, Silvana Pedatella   +6 more
wiley   +1 more source

Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro

, 2017
Yuh-Hwa Liu,1,2,* Yeh-Lin Lu,3,* Der-Zen Liu,4 Wen-Chi Hou5 1Division of Gastroenterology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; 2Department of General Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 3Department
Hou WC, Liu DZ, Liu YH, Lu YL
core  

Programmable Site‐Selectivity: pH‐Modulated Triazine–Thiol Exchange for Site‐ and Chemoselective Cysteine Labeling

ChemistryEurope, Volume 3, Issue 5, September 18, 2025.
A pH‐programmable site‐selective cysteine modification in peptides is reported using a triazine–thiol exchange, termed TriTEx. At acidic pH, internal cysteines are targeted while preserving N‐terminal sites; at neutral pH, N‐terminal cysteines are selectively modified via an irreversible S–N shift.
Katerina Gavriel, Daniel Deißenbeck, Thomas J. Rutjes, Daniëlle W. T. Geers, Jan Meisner, Kevin Neumann   +5 more
wiley   +1 more source

Semicarbazide-sensitive amine oxidase substrates in obesity and diabetes

, 2010
L'obésité et le diabète sont de sérieux problèmes de santé dans les pays développés. Le développement de médicaments qui pourraient normaliser un métabolisme glucidique alteré est donc une grande nécessité actuelle.
Iffiu-Soltész, Zsuzsa
core  

Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor

ChemBioChem, Volume 26, Issue 16, September 12, 2025.
This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau, Wolf‐Dieter Fessner, Zvjezdana Findrik Blažević, Michael Breuer   +3 more
wiley   +1 more source

Navigating Nitrofuran Challenges in Farmed Prawn (Macrobrachium rosenbergii): Strengthening Safety and Export Potentials in Bangladesh

Reviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Nitrofuran metabolites, including semicarbazide, pose significant risks to food safety, particularly in the aquatic industry. Bangladesh's shrimp industry faced major challenges due to nitrofuran contamination, leading to a voluntary export suspension to the European Union (EU).
S. M. Nazmul Alam
wiley   +1 more source