Results 61 to 70 of about 818 (181)

Synthesis of Novel Dihydropyridine‐Iminium Salts Containing a Selenazine Core

open access: yesAsian Journal of Organic Chemistry, Volume 14, Issue 10, October 2025.
An efficient method to develop novel dihydropyrido[3,2‐e][1,3]selenazines iminium salts. A comparative study of the key reagent selenourea towards thiourea and urea was carried out to assess the contribution of chalcogen to the pathway. DFT (density functional theory) calculations have predicted the optimized minimum energy structure for the hybrid ...
Reinier Lemos   +6 more
wiley   +1 more source

Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine - synthesis, cytostatic, antiviral and antioxidative studies

open access: yes, 2013
A series of novel 1,4-substituted semicarbazides 5a-g with a primaquine moiety bridged by a carbonyl group at position 1 and a cycloalkyl, aryl, benzyloxy or hydroxy substituent at position 4 were prepared and biologically evaluated.
Kralj, Marijeta   +8 more
core   +1 more source

Programmable Site‐Selectivity: pH‐Modulated Triazine–Thiol Exchange for Site‐ and Chemoselective Cysteine Labeling

open access: yesChemistryEurope, Volume 3, Issue 5, September 18, 2025.
A pH‐programmable site‐selective cysteine modification in peptides is reported using a triazine–thiol exchange, termed TriTEx. At acidic pH, internal cysteines are targeted while preserving N‐terminal sites; at neutral pH, N‐terminal cysteines are selectively modified via an irreversible S–N shift.
Katerina Gavriel   +5 more
wiley   +1 more source

Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor

open access: yesChemBioChem, Volume 26, Issue 16, September 12, 2025.
This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau   +3 more
wiley   +1 more source

Navigating Nitrofuran Challenges in Farmed Prawn (Macrobrachium rosenbergii): Strengthening Safety and Export Potentials in Bangladesh

open access: yesReviews in Aquaculture, Volume 17, Issue 4, September 2025.
ABSTRACT Nitrofuran metabolites, including semicarbazide, pose significant risks to food safety, particularly in the aquatic industry. Bangladesh's shrimp industry faced major challenges due to nitrofuran contamination, leading to a voluntary export suspension to the European Union (EU).
S. M. Nazmul Alam
wiley   +1 more source

Synthesis and Structural Studies of Aza Analogues of Functionalized Amino Acids:  New Anticonvulsant Agents

open access: yes, 2016
We have reported that functionalized amino acids 1 display potent anticonvulsant activities in mice and rats, and that the activity resides primarily in the d-isomer.
Harold Kohn (1333722)   +3 more
core   +1 more source

Submonomer Synthesis of A Hybrid Peptoid–Azapeptoid Library

open access: yes, 2016
We recently reported efficient conditions for the synthesis of N-azapeptoid libraries via the typical submonomer strategy of peptoid synthesis but that substitutes N-acyl hydrazides for primary amines as submonomers.
Bani Kanta Sarma (2037217)   +1 more
core   +1 more source

Mechanochemical synthesis of coumarin semicarbazides

open access: yes
Potreba za ekološki prihvatljivim kemijskim postupcima dovela je do velike zainteresiranosti za područje mehanokemije. U ovom radu kumarinski semikarbazidi su sintetizirani pomoću mehaničke energije u kugličnom mlinu bez korištenja otapala i ispitana je ...
Milić, Toni
core   +1 more source

Efficient synthesis of tri- and difluoroacetyl hydrazides as useful building blocks for non-symmetrically substituted, fluoroalkylated 1,3,4-oxadiazoles [PDF]

open access: yes, 2016
A convenient and efficient approach to 2-arylamino-5-fluoroalkyl-1,3,4-oxadiazoles has been established via heterocyclization of tri- and difluoroacetylated thiosemicarbazides using dicyclohexylcarbodiimide.
Obijalska, Emilia   +3 more
core   +1 more source

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