Results 51 to 60 of about 818 (181)

Acid Hydrazide: A Potential Reagent for the Synthesis of Semicarbazones

open access: yes, 2018
Complex semicarbazone derivatives were successfully synthesized from substituted semicarbazides in acidic ethanol upon heating in the presence of aldehyde.
Nath, Amit Ranjan   +1 more
core   +1 more source

Enhancing Open‐Circuit Voltage and Fill Factor in Sn‐Based Perovskite Solar Cells: Challenges and Opportunities for Sustainable Photovoltaics

open access: yesSusMat, Volume 5, Issue 6, December 2025.
This review summarizes advances in tin (Sn)‐based perovskite solar cells, a promising lead‐free alternative. It examines the main causes of Voc and fill factor losses, including Sn2+ oxidation, undercoordinated sites, and deep‐level traps. Strategies such as molecular coordination, surface passivation, compositional tuning, interface engineering, and ...
Padmini Pandey   +4 more
wiley   +1 more source

Development of a Partial Proteolysis Targeting Chimera Library Based on Achiral Cereblon E3 Ligase Ligands and its Application for Bruton's Tyrosine Kinase Degraders

open access: yesChemMedChem, Volume 20, Issue 22, November 18, 2025.
A partial proteolysis targeting chimera (PROTAC) library bearing achiral phenyl dihydrouracil cereblon ligands is prepared. It is then applied to the rapid development of a full PROTAC library targeting Bruton's tyrosine kinase, which can be directly used for screening.
Chelsi M. Almodóvar‐Rivera   +5 more
wiley   +1 more source

Anticonvulsant 4-aryl semicarbazides & thioureas

open access: yes, 1985
Among a series of anticonvulsant 1-aryl semicarbazides, 1-(3-5-bistrifluoromethyl)phenylsemicarbazide, C3884-Go(11) and its 4-methyl derivative, C 3165-Go (12) showed good activity of long duration in the electroshock test in mice and rats.
Rajappa, S.   +3 more
core   +1 more source

STUDY OF THE REACTION BETWEEN CARBAMOYL AZIDE OF α-N-PROTECTED AMINO ACIDS AND HYDRAZINE MONOHYDRATE

open access: yes, 2011
Two simple and efficient synthetic methods for the preparation of semicarbazide amino acid derivatives are reported. The procedures involve reaction between the carbamoyl azides of alpha-N-protected amino acids and hydrazine monohydrate: 4 ...
ESPOSITO, Gennaro   +3 more
core   +1 more source

Convulsant Effects of Semicarbazide in Epileptic Monkeys.

open access: yesExperimental Biology and Medicine, 1956
Summary(1) Threshold convulsant dosages to rapid intravenous injection of semicarbazide were significantly lower in chronically epileptic monkeys than in normal unoperated controls. (2) Clinical seizures following intravenous injection of threshold convulsant doses of semicarbazide occurred after a latent period of 2 to 3 1/2 hours. With suprathreshold
L M, KOPELOFF, J G, CHUSID, N, KOPELOFF
openaire   +2 more sources

Hypothalamic Astrocytes Exhibit Glycolytic Features Making Them Prone for Glucose Sensing

open access: yesGlia, Volume 73, Issue 11, Page 2253-2272, November 2025.
Main Points Hypothalamic astrocytes versus cortical astrocytes: are more glycolytic due to high Pkm2, Glut1 and Mct4 expression do not exhibit glutamate‐induced glycolysis detect glucose concentration variations via an AMPK sensor with altered lactate production.
Sarah Geller   +11 more
wiley   +1 more source

Síntese de novos derivados de 1-(7-cloro-4-quinolinil) tiossemicarbazidas e semicarbazidas como potencias agentes antibacterianos e antiparasitários [PDF]

open access: yes, 2011
This work, entitled “Synthesis of novel derivatives of 1-(7-chloro-4-quinolinyl) thiosemicarbazides and semicarbazides as potencial antibacterial and antiparasitic agents” describes the synthesis of new derivatives of 1-(7-chloro-4-quinolinyl ...
Machado, Rafael Carvalhaes
core  

Carbonic Anhydrase Inhibitors: Design, Synthesis, and Biological Evaluation of Novel Sulfonyl Semicarbazide Derivatives

open access: yes, 2016
A series of novel sulfonyl semicarbazides 5–13 was designed, synthesized, and evaluated for human carbonic anhydrase (hCA) inhibition. The new sulfonyl semicarbazides were tested against a panel of hCA isoforms I, II, IX, and XII, using acetazolamide ...
Prashant S. Kharkar (1780549)   +4 more
core   +1 more source

Batch Synthesis of Primaquine Diphosphate Anti‐Malarial Drug

open access: yesChemistry – A European Journal, Volume 31, Issue 59, October 22, 2025.
According to the WHO, a child under the age of five dies every 2 minutes from malaria in Africa. It is therefore paramount that access and availability of anti‐malarial drugs must be improved. We report a process for the synthesis of Primaquine Diphosphate, where key intermediates were obtained in a much shorter reaction time compared to processes ...
Faith M. Akwi   +2 more
wiley   +1 more source

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