Convulsant Effects of Semicarbazide in Epileptic Monkeys.
Summary(1) Threshold convulsant dosages to rapid intravenous injection of semicarbazide were significantly lower in chronically epileptic monkeys than in normal unoperated controls. (2) Clinical seizures following intravenous injection of threshold convulsant doses of semicarbazide occurred after a latent period of 2 to 3 1/2 hours. With suprathreshold
L M, KOPELOFF, J G, CHUSID, N, KOPELOFF
openaire +2 more sources
Synthesis and RP HPLC studies of biologically active semicarbazides and their cyclic analogues 1,2,4-triazol-3-ones [PDF]
: The retention behaviour of semicarbazides and their cyclic analogues 1,2,4-triazol-3-ones, has been investigated by RP-8, RP-18 and IAM HPLC. The structures of new derivatives were proved by elemental analyses, IR, (1)H NMR and (13)C NMR spectroscopy ...
Bogdan Senczyna +2 more
core +1 more source
Hazelnut: Explorations toward the Biocatalytic Synthesis of its Aroma Precursor
This article proposes a biosynthetic route for synthesizing filbertone, the principal flavor compound of hazelnut, through a multienzyme cascade. The pathway uses D‐amino acid oxidase, threonine deaminase, and a regioselective transketolase from Geobacillus stearothermophilus to produce a sustainable, natural hazelnut aroma precursor, addressing ...
Mireia Salvadó‐Pau +3 more
wiley +1 more source
“In Vitro Antimicrobial Activity and DNA Cleavage Studies: Synthesis and Characterization of Novel M(II) Complexes with O, N, O donor Schiff Base Ligand Derived from Phenylpropanehydrazide” [PDF]
Three new ternary complexes of general formulation [M(L)n] (1–3), where L=N`-(5-chloro-2-hydroxybenzylidine)-3- phenylpropanehydrazide; n=2;M= Cu, Ni, Zn, complexes are synthesized, characterized by various physicochemical and UV-Vis, FTIR, 1H NMR and ...
Chetana, P.R. +3 more
core
ABSTRACT Nitrofuran metabolites, including semicarbazide, pose significant risks to food safety, particularly in the aquatic industry. Bangladesh's shrimp industry faced major challenges due to nitrofuran contamination, leading to a voluntary export suspension to the European Union (EU).
S. M. Nazmul Alam
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The Preparation and Pyrolysis of 2-methyl-4-alkyl(aryl)semicarbazides [PDF]
The purpose of the research described in this thesis was twofold. Attempts were made to prepare several 4-alkyl (aryl)-2-methylsemicarbazides, many of which had not been prepared previously.
Sherwood, Bob Edwin
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Partially Biobased Self‐Repairing Poly(Aspartic Ester Polyurea) Coatings
Sustainable self‐healing PAEU coatings, containing various amounts of disulfide derived from poly(aspartic esters) and biobased polyisocyanates, were created. ABSTRACT Poly(aspartic ester polyurea) (PAEU) coating systems, which feature an uncatalyzed and solventless reaction, have attracted attention as a more environmentally friendly, nonreactive ...
Sevilay Dural +2 more
wiley +1 more source
Kommunale Kläranlagen gelten als Haupteintragspfad organischer Mikroschadstoffe in die aquatische Umwelt. Ein Großteil der Arzneimittelrückstände und Industriechemikalien wird in Kläranlagen nicht oder nur teilweise entfernt. Um einen qualitativ höheren Kläranlagen‐Ablauf zu erzeugen, wird eine Kombination aus hybridem Teilstrom‐Membran‐Bioreaktor mit ...
Maximilian Werner +4 more
wiley +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law +6 more
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The Latest Advances in Mechanically Robust Self‐Healing Polyurea Based on Dynamic Chemistry
Solving the contradiction between strength, toughness, and self‐healing properties is extremely important to realize the breakthrough of polyurea applications. This review summarizes and discusses common strategies for the preparation of high‐performance and self‐healing polyurea materials based on dynamic chemistry, providing molecular‐level insights ...
Yujia Hao, Guangming Zhu
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