Results 31 to 40 of about 878 (177)
Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang +3 more
wiley +2 more sources
Anticonvulsant 4-aryl semicarbazides & thioureas
Among a series of anticonvulsant 1-aryl semicarbazides, 1-(3-5-bistrifluoromethyl)phenylsemicarbazide, C3884-Go(11) and its 4-methyl derivative, C 3165-Go (12) showed good activity of long duration in the electroshock test in mice and rats.
Rajappa, S. +3 more
core +2 more sources
ω‐Hydroxy and ω‐oxo acids are precursors to lactones, polyesters, and nylon‐6, yet selective interconverting enzymes remain scarce. Clostridium viride supplies two iron alcohol dehydrogenases: Cvir‐Hbd2, restricted to C4, and the genomic singleton Cvir‐Hvd, spanning C5–C12 substrates.
Tarik Begic +7 more
wiley +1 more source
Čudesna molekula benzotriazol [PDF]
In this paper, a review of reactions with benzotriazole as synthetic auxiliary is given. In contrast to most other azoles, benzotriazole reacts with phosgene in molar ratio 1:1 yielding carboxylic acid chloride (BtcCl, 1), which readily reacts with ...
Zorc, B., Butula, I.
doaj
XXXVII.—Formation of oxytriazoles from semicarbazides [PDF]
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Young, George +1 more
openaire +2 more sources
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
Abstract Purpose Meniscal injuries are among the most common knee disorders and a major risk factor for osteoarthritis. Although meniscectomy provides short‐term symptom relief, it irreversibly alters joint biomechanics, underscoring the need for regenerative strategies.
Andrea Ferrero +9 more
wiley +1 more source
In this work, we successfully synthesized a library of novel N‐amidinyl‐benzodiazaborines, showing how these heteroaryl guanyl hydrazones are able to stabilize the retromer, a protein complex involved in the disposal of misfolded and aggregated proteins, whose malfunction is observed in multiple neurodegenerative diseases.
Alessandro Dimasi +10 more
wiley +1 more source
Department of Chemistry, Lucknow University, Lucknow-226 007 Division of Experimental Medicine, C. D. R. I., Lucknow Manuscript received 9 March 1981, revised 18 March 1982 accepted 12 August 1982 Search for New Hypoglycemic Agents.
(Miss) KIRAN BALA GUPTA +2 more
core +1 more source
Designed Lewis Acid–Base Passivation for High Performance Perovskite Solar Cells
ABSTRACT Silicon's high cost and long energy payback time remain major barriers to the global expansion of solar power. In contrast, metal–halide perovskites offer abundant, solution‐processable absorbers, and have achieved efficiencies of 25%–30%, positioning them as strong competitors to silicon.
Afna Manaf +4 more
wiley +1 more source

