Results 31 to 40 of about 818 (181)

ANTAGONISM OF THE SPINAL ACTION OF DIAZEPAM BY SEMICARBAZIDE [PDF]

open access: yesBritish Journal of Pharmacology, 1974
In spinal unanaesthetized cats, pretreatment with semicarbazide (200 mg/kg) 2–4.5 h prior to the administration of diazepam (1–4 mg/kg) completely blocked the enhancement of the segmental dorsal root reflex by the latter compound. Pyridoxine hydrochloride (200 mg/kg), given 3.5 h after semicarbazide, restored the spinal effect of diazepam administered ...
N R, Banna, S J, Jabbur, N E, Saadé
openaire   +2 more sources

Ribosomal Synthesis of Topologically Defined Thioisoindole‐Bridged Bicyclic Peptides

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
A flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Yue Zhang   +3 more
wiley   +2 more sources

Advances in organic UV filters for sunscreens over the past decade

open access: yesPhotochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon   +4 more
wiley   +1 more source

Novel semicarbazides and ureas of primaquine with bulky aryl or hydroxyalkyl substituents: Synthesis, cytostatic and antioxidative activity

open access: yes, 2014
Novel primaquine semicarbazides 7a-l and ureas 9a-g with modified benzhydryl, trityl, phenyl or hydroxyalkyl substituents were prepared and evaluated for cytostatic and antioxidative activities.
Cindrić, M.   +9 more
core   +1 more source

N‐Amidinyl‐Benzodiazaborines as Novel Boron‐Based Scaffolds: Synthesis and Application in Retromer Stabilization

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
In this work, we successfully synthesized a library of novel N‐amidinyl‐benzodiazaborines, showing how these heteroaryl guanyl hydrazones are able to stabilize the retromer, a protein complex involved in the disposal of misfolded and aggregated proteins, whose malfunction is observed in multiple neurodegenerative diseases.
Alessandro Dimasi   +10 more
wiley   +1 more source

Search for New Hypoglycemic Agents. Part-VII : Coumarinylsulphonyl Ureas, Semicarbazides and Semicarbazones

open access: yes, 1982
Department of Chemistry, Lucknow University, Lucknow-226 007 Division of Experimental Medicine, C. D. R. I., Lucknow Manuscript received 9 March 1981, revised 18 March 1982 accepted 12 August 1982 Search for New Hypoglycemic Agents.
(Miss) KIRAN BALA GUPTA   +2 more
core   +1 more source

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra   +11 more
wiley   +1 more source

Čudesna molekula benzotriazol [PDF]

open access: yesKemija u Industriji, 2007
In this paper, a review of reactions with benzotriazole as synthetic auxiliary is given. In contrast to most other azoles, benzotriazole reacts with phosgene in molar ratio 1:1 yielding carboxylic acid chloride (BtcCl, 1), which readily reacts with ...
Zorc, B., Butula, I.
doaj  

Toxicological Evaluation of the Undesirable Components in Processed Infant Foods Using Artificial Intelligence

open access: yesFuture Postharvest and Food, Volume 3, Issue 2, Page 185-205, June 2026.
The detection of toxins in baby food using artificial intelligence. ABSTRACT Infant foods and baby formulas are becoming increasingly popular across the globe owing to their ease of consumption and nutritional value specific to infants. Impurities may find their way into the food chain at any point from the acquisition of raw materials to final ...
Poornima Singh   +3 more
wiley   +1 more source

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