Results 41 to 50 of about 818 (181)

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

A NOTE ON THE STABILITY OF SOME SUBSTITUTED SEMICARBAZIDES

, 1945
Recently Baker and Gilbert (J. Amer. Chem. Soc, 1942, 64, 2777) have studied the kinetics of the transformation of hydrazine cyanate into semicarbazide and also of the conversion of semicarbazide into hydrazine cyanate.
T. N. GHOSH
core   +1 more source

On‐Demand Chemically Degradable Hydrogels for Biological Applications

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
This review explores the mechanisms and kinetics of chemically induced on‐demand degradation in hydrogels designed for painless dressing removal and traceless dissolution across various biological applications. Covalent bond cleavage and noncovalent disruption triggers are compared, highlighting opportunities for load‐bearing scaffolds with faster ...
Xinyi Sheng, Justin Kim
wiley   +1 more source

Enantioselective Growth of Chiral Serine‐Induced β‐Ag2Se Crystals from an Organoselenium Compound

Advanced Functional Materials, Volume 36, Issue 22, 16 March 2026.
Chiral amino acids direct the enantioselective crystallization of β‐Ag2Se nanocrystals from an organoselenium precursor. L‐ and D‐serine induce distinct morphologies and opposite homochiral adsorption preferences, transferring molecular handedness into the inorganic lattice.
Matan Oliel, Yarden B. Moshe, Gil Otis, Dana D. Medina, Yitzhak Mastai, Subhomoy Das   +5 more
wiley   +1 more source

XXXVII.—Formation of oxytriazoles from semicarbazides [PDF]

J. Chem. Soc., Trans., 1898
n ...
Young, George, Stockwell, Benjamin Mitchell   +1 more
openaire   +2 more sources

Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds

ChemMedChem, Volume 21, Issue 2, January 2026.
Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley   +1 more source

NEW METAL-CONTAINING POLY(URETHANE-SEMICARBAZIDES) ON THE BASIS OF PYRIDINE DERIVATIVES

, 2019
The growth of science and technology of polyurethanes leads to the development of new materials with more desirable properties. Modification of polyurethane (PU) by incorporating metal and functional groups are used extensively to improve various ...
Kositsyna, Olena, Olena Kositsyna, Kositsyna, Olena; Oles Honchar Dnipro National University   +2 more
core   +1 more source

Solid-Phase Synthesis of Hybrid 2,5-Diketopiperazines Using Acylhydrazide, Carbazate, Semicarbazide, Amino Acid, and Primary Amine Submonomers

, 2020
We report the solid-phase synthesis of N,N′-di­(acylamino)-2,5-diketopiperazine, an acylhydrazide-based conformationally rigid 2,5-DKP scaffold having exocyclic N–N bonds.
Abdur Rahim (5699147), Kalpita Baruah (8435520), Bani Kanta Sarma (2037217), Jugal Kishore Rai Deka (8435523), Biswajit Sahariah, Jugal Kishore Rai Deka, Abdur Rahim, Kalpita Baruah, Biswajit Sahariah (5699150), Bani Kanta Sarma   +9 more
core   +3 more sources

Some semicarbazide derivatives and their antimicrobial activity

Communications, Faculty Of Science, University of Ankara Series B Chemistry and Chemical Engineering, 1993
Various semicarbazides and thiosemicarbazides (1-5) and their cyclised products, triazoles, oxadiazoles and thiadiazoles (6-9) have been reported to possess antibacterial, antitubercular and antifungal activities. Based on these findings it w as of interest to prepare some new arylsemicarbazide and arylthiosemicarbazide derivatives and to evaluate ...
F. Abd EL-AZEEM, A. H. MANDOUR, İbrahim İmam ISMAIL   +2 more
openaire   +2 more sources

Influence of Material Viscosity on the Properties of Extruded High‐Consistency Silicone Rubber Foam Profiles

Advances in Materials Science and Engineering, Volume 2026, Issue 1, 2026.
High‐consistency silicone rubbers can be foamed with various chemical and physical blowing agents. However, due to the toxic and, therewith, harmful effects of chemical blowing agents, physical blowing agents are becoming increasingly important. In this thesis, the influence of the viscosity adjusted via the silica content of different high‐consistency
Timo Hofmann, Ralf-Urs Giesen, Hans-Peter Heim, Mohammad Rezwan Habib   +3 more
wiley   +1 more source