Results 11 to 20 of about 6,596 (245)
Ribosomal Synthesis of Topologically Defined Thioisoindole-Bridged Bicyclic Peptides. [PDF]
Angew Chem Int Ed EnglA flexible in vitro translation (FIT) system‐based strategy for ribosomal synthesis of thioisoindole‐bridged bicyclic (TiB) peptides is developed. The flexizyme substrate Ac‐Ala(NtBA)Sc‐CME is efficiently incorporated into FIT to generate ribosomal peptides bearing N‐terminal Ac‐Ala(NtBA)Sc as the cyclization handle, which after mild deprotection ...
Zhang Y, Vinogradov AA, Sun Y, Suga H.
europepmc +3 more sources
Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. [PDF]
, 2015 BackgroundIt is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage.
Cooper, Arthur JL +8 more
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Molecules, 2021 Two new series of betulin derivatives with semicarbazone (7a–g) or thiosemicarbazone (8a–g) groups at the C-28 position were synthesized. All compounds were evaluated for their in vitro cytotoxicities in human hepatocellular carcinoma cells (HepG2 ...
Jiafeng Wang +8 more
doaj +1 more source
The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives
Memorias do Instituto Oswaldo Cruz, 2013 Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method.
Marina Azevêdo Souza +11 more
doaj +3 more sources
Crystal structure of 4-hydroxy-3-meth-oxybenzaldehyde 4-methylthiosemi-carbazone methanol monosolvate [PDF]
, 2015 BRSF thanks CNPq/UFS for the award of a PIBIC scholarship.Peer reviewedPublisher ...
Beck, Johannes +3 more
core +4 more sources
Molecules, 2020 The four compounds, namely: 5-nitro-2-furaldehyde thiosemicarbazone (1); 5-nitro-2-thiophene thiosemicarbazone (2); 5-nitro-2-furaldehyde semicarbazone (3); and 5-nitro-2-thiophene semicarbazone (4) were synthesized and crystallized.
Marcin Swiatkowski +4 more
doaj +1 more source
E-Journal of Chemistry, 2009 Co, Ni and Cu complexes have been prepared by reacting metal chloride with 4-chlorobenzaldehyde oxime, 4-methylbenzaldehyde oxime, 4-nitrobenzaldehyde oxime, 4-chlorobenzaldehyde semicarbazone, 4-methyl- benzaldehyde semicarbazone, 4-nitrobenzaldehyde ...
Majed M. Hania
doaj +1 more source
Crystal structure of 2-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-N-phenylhydrazinecarboxamide
Acta Crystallographica Section E: Crystallographic Communications, 2019 The title compound, C17H17N3O, crystallizes with two independent molecules in the asymmetric unit. The semicarbazone moieties of these independent molecules (I and II) are essentially planar [maximum deviation of 0.042 (1) Å in molecule I and 0.041 (1) Å
S. R. Saritha +4 more
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Pharmaceuticals, 2022 The rapid development of resistance by ureolytic bacteria which are involved in various life-threatening conditions such as gastric and duodenal cancer has induced the need to develop a new line of therapy which has anti-urease activity.
Ayesha Naseer +7 more
doaj +1 more source
Semikarbazon – svestrani farmakofor u dizajniranju antikonvulziva [PDF]
, 2012 During the last fifteen years semicarbazones have been extensively investigated for their anticonvulsant properties. 4-(4-Flurophenoxy) benzaldehyde semicarbazone (C0102862, V102862) has been discovered as a lead molecule and is being developed as a ...
SURENDRA NATH PANDEYA
core +2 more sources