Results 211 to 220 of about 6,596 (245)

Proteasome inhibition by peptide-semicarbazones

Bioorganic & Medicinal Chemistry, 2008
Peptide-semicarbazones derived from Z-Trp-Trp-Phe-aldehyde inhibit the chymotryptic activity of the human proteasome at nanomolar concentrations, but are less active in a NFkappaB reporter gene assay. Cyclic semicarbazones, in contrast, combine a strong inhibitory effect on the enzyme with an inhibition of NFkappaB signaling in the nanomolar range.
Johann, Leban, Marcus, Blisse, Babett, Krauss, Sandra, Rath, Roland, Baumgartner, Markus H J, Seifert   +5 more
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Immunosuppressive effects of Ovalicin-semicarbazone

Agents and Actions, 1974
Ovalicin-semicarbazone suppresses antibody-formation in mice and in other species as measured in the plaque-forming cell and haemagglutination tests. It further impairs cell-mediated immunity as assayed by: homograft reaction and immune cytolysis of tumour target cells in mice, experimental allergic encephalomyelitis in rats, and the tuberculin ...
J F, Borel, S, Lazáry, H, Stähelin
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4-Phenylbutan-2-one semicarbazone

Acta Crystallographica Section C Crystal Structure Communications, 2000
The title compound, C(11)H(15)N(3)O, crystallizes with two molecules in the asymmetric unit, which are held together by an extended network of hydrogen bonds. It is remarkable that only five of the six theoretically possible hydrogen bonds are formed.
A, Degen, S, Rühl, M, Bolte
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ChemInform Abstract: FORMALDEHYDE SEMICARBAZONE

Chemischer Informationsdienst, 1982
AbstractAzo‐dicarbonsäurediamid (I) reagiert mit Diazomethan (II) zum bisher unbekannt gewesenen Formaldehyd‐semicarbazon (III).
M. POMERANTZ, S. BITTNER, S. B. KHADER
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Anticonvulsant Activities of 4–Bromobenzaldehyde Semicarbazone

Epilepsia, 1994
Summary:Some of the properties of 4–bromobenzalde‐hyde semicarbazone (compound IV), a prototype molecule of a new class of anticonvulsants, aryl semicarbazones, are described. Compound IV demonstrated activity in the maximal electroshock (MES) and subcutaneous pentylenetetrazol (scPTZ) tests in mice, with low neurotoxicity.
J R, Dimmock, G B, Baker
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ChemInform Abstract: Semicarbazones and Thiosemicarbazones. Part 12. Crystal Structure of Salicylaldehyde Semicarbazone

ChemInform, 1991
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
J. VALDES‐MARTINEZ, R. A. TOSCANO, R. SALCEDO, R. CEA‐OLIVARES, A. MELENDEZ   +4 more
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4-Sulphamoylphenyl semicarbazones with anticonvulsant activity

Il Farmaco, 2004
A series of 4-sulphamoylphenyl semicarbazone derivatives were prepared starting from sulphanilamide and screened for anticonvulsant activity. The results indicated that greater protection was obtained in the maximal electroshock screen (MES) and subcutaneous strychnine (scSTY) than the subcutaneous pentylenetetrazole (scPTZ) tests.
P, Yogeeswari, D, Sriram, S N, Pandeya, J P, Stables   +3 more
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Controlled Ligand Deprotonation in Lanthanide Chelates with Asymmetric Semicarbazone/Benzoylhydrazone or Semicarbazone/Thiosemicarbazone Coordination Spheres

Inorganic Chemistry, 2005
Asymmetric, potentially pentadentate ligands (H(2)L(3)) are formed by subsequent condensation of a semicarbazide and benzoylhydrazine on 2,6-diacetylpyridine. Two equivalents of H(2)L(3) reacts with CeCl(3).7H(2)O, Ce(SO(4))(2).4H(2)O, or EuCl(3).6H(2)O under formation of [Ln(III)(HL(3))(2)](+) cations (Ln = Ce, Eu) with exclusive deprotonation of the ...
Alexander, Jagst, Agustin, Sanchez, Ezequiel M, Vazquez-Lopez, Ulrich, Abram   +3 more
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Antituberculous Activity of Some Aryl Semicarbazone Derivatives.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Dharmarajan, Sriram, Perumal, Yogeeswari, Rathinasabapathy, Thirumurugan   +2 more
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ChemInform Abstract: HETEROCYCLISCHE SEMICARBAZONE UND THIOSEMICARBAZONE 28. MITT. ISOMERIE DES ISATIN‐BETA‐SEMICARBAZONS

Chemischer Informationsdienst, 1973
AbstractDie Reaktion der Isatine (Ia) mit äquimolaren Mengen von Semicarbazidhydro‐ Chlorid in siedender wäßriger Lösung liefert quantitativ Gemische der Monosemicarbazone (IIa) und (IIIa).
A. B. TOMCHIN, I. S. IOFFE, V. V. TRET'YAKOVA, YU. V. LEPP, A. I. KOL'TSOV   +4 more
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