Results 21 to 30 of about 6,596 (245)

Crystal structure and Hirshfeld surface analysis of (E)-1-[(4,7-dimethylquinolin-2-yl)methylidene]semicarbazide dihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2018
In the title compound, C13H14N4O·2H2O, the organic molecule is almost planar. In the crystal, the molecules are linked by O—H...O, N—H...O and O—H...N hydrogen bonds, forming a two-dimensional network parallel to (10\overline{1}).
Ercan Aydemir, Sevgi Kansiz, Necmi Dege, Hasan Genc, Snizhana V. Gaidai   +4 more
doaj   +1 more source

Thiazole, triazole, thio- and semicarbazone derivatives - Promising moieties for drug development for the treatment of tuberculosis

European Journal of Medicinal Chemistry Reports, 2021
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB).
Cauê Benito Scarim, Fernando Rogério Pavan   +1 more
doaj   +1 more source

3D printed fluidics with embedded analytic functionality for automated reaction optimisation [PDF]

, 2017
Additive manufacturing or ‘3D printing’ is being developed as a novel manufacturing process for the production of bespoke micro- and milliscale fluidic devices.
Capel, Andrew J., Christie, Steven D.R., Edmondson, Steve, Goodridge, Ruth D., Harding, Matthew J., Harris, Russell A., Li, Yuqi, Weaver, George W., Wright, Andrew   +8 more
core   +5 more sources

Microwave-assisted synthesis and antibacterial and pesticidal activity studies of aluminum(III) and gallium(III) complexes with a bioactive Schiff base

Main Group Metal Chemistry, 2011
Biologically potent complexes of aluminum(III) and gallium(III) derived from semicarbazone of 3-acetylcoumarin have been synthesized under microwave irradiation and investigated using a combination of microanalytical analysis, melting point, ultraviolet ...
Singh Nirmala, Rastogi Shobha, Singh R.V.   +2 more
doaj   +1 more source

Evaluating 5-nitrofurans as trypanocidal agents [PDF]

, 2013
The nitroheterocycle nifurtimox, as part of a nifurtimox-eflornithine combination therapy, represents one of a limited number of treatments targeting Trypanosoma brucei, the causative agent of human African trypanosomiasis.
Alvarez, G, Bot, C, Cerecetto, H, Di Maio, D, Gonzalez, M, Hall, BS, WILKINSON, SR   +6 more
core   +1 more source

Antimicrobial and pesticidal activity of some organogermanium(IV) complexes synthesized under microwave irradiation

Main Group Metal Chemistry, 2011
Reactions of 2-hydroxy-N-phenylbenzamide with semicarbazide hydrochloride and thiosemicarbazide resulted in the formation of new ketimines, semicarbazone and thiosemicarbazone of 2-hydroxy-N-phenylbenzamide, respectively.
Dawara Latika, Singh Davendra, Singh Ran Vir   +2 more
doaj   +1 more source

(1Z)-1-(2,4-Dichlorophenyl)ethan-1-one semicarbazone

Acta Crystallographica Section E, 2009
In the title compound, C9H9Cl2N3O, the semicarbazone group is approximately planar, with an r.m.s deviation from the mean plane of 0.011 (2) Å.
Hoong-Kun Fun, Kasthuri Balasubramani, A. M. Vijesh, Shridhar Malladii, Arun M. Isloor   +4 more
doaj   +1 more source

An Enabling Peptide Ligation Induced by Thiol-Salicylaldehyde Ester for Chemical Protein Synthesis. [PDF]

Adv Sci (Weinh)
A novel and powerful peptide ligation between peptide TSAL esters and peptides are reported bearing N‐terminal cysteine/penicillamine that enables effective coupling reactions even at the most sterically hindered Pro‐Val site. This new method will bring more opportunities and valuable options for the future convergent synthesis of otherwise ...
Li C, Ma W, Jin K.
europepmc   +2 more sources

Continuous Flow Synthesis of Nitrofuran Pharmaceuticals Using Acetyl Nitrate

Angewandte Chemie, Volume 137, Issue 25, June 17, 2025.
A robust, automated continuous flow system enables safe, high‐yield nitration of furfural to key nitrofuran intermediates using in situ acetyl nitrate generation. Demonstrated on representative essential World Health Organization (WHO) active pharmaceutical ingredients (API), this innovative open‐source platform ensures rapid synthesis, enhanced safety,
Hubert Hellwig, Loïc Bovy, Kristof Van Hecke, Cornelis P. Vlaar, Rodolfo J. Romañach, Md. Noor‐E‐Alam, Allan S. Myerson, Torsten Stelzer, Jean‐Christophe M. Monbaliu   +8 more
wiley   +2 more sources

(Z)-1-(2,5-Dichloro-3-thienyl)ethanone semicarbazone

Acta Crystallographica Section E, 2009
The title molecule, C7H7Cl2N3OS, is approximately planar [maximum deviation = 0.062 (1) Å]. Short intermolecular distances between the centroids of the five-membered rings [3.5340 (8) Å] indicate ...
Hoong-Kun Fun, Ching Kheng Quah, A. M. Vijesh, Chitrakar Hegde, Arun M. Isloor   +4 more
doaj   +1 more source