Results 51 to 60 of about 9,688 (167)

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Unusual renal and colonic mass: Description of a rare case

Indian Journal of Medical and Paediatric Oncology, 2019
Seminoma is a germ cell tumor which accounts for approximately 40% of all germ cell tumors. Testicular seminoma is usually localized to the testis, and in 25% of cases, lymph node metastasis is seen. However, rarely, it can metastasize to visceras.
Manika Khare, Arvind Ahuja, Minakshi Bhardwaj, Nikhil Khattar   +3 more
doaj   +1 more source

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Seminoma mediastínico: A propósito de um caso clínico

Revista Portuguesa de Pneumologia, 2008
Resumo: A propósito de um caso clínico, os autores fazem uma breve revisão da clínica, diagnóstico e tratamento do seminoma com localização mediastínica.Rev Port Pneumol 2008; XIV (5): 705-708 Abstact: In reference to a clinical report, the ...
José Roberto Silva, Adelino Carragoso, Orlando Gaspar   +2 more
doaj   +1 more source

Unusual case of classic testicular seminoma in a 90-year-old patient: a case report

Journal of Medical Case Reports, 2020
Background Seminoma is the most common subtype of testicular cancer and occurs most commonly in patients aged 30–49 years, but decreases to a very low level in men in their 60s or older. Case presentation A 90-year-old Syrian man with a 6-year history of
Ahmad Al-Mousa, Mohammad Nour Shashaa, Mohamad Shadi Alkarrash, Mohamad Alkhamis, Lina Ghabreau, Mouhsen Dandal   +5 more
doaj   +1 more source

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Foreign-body granuloma mimicking post-chemotherapy residual seminoma: A case of true-negative findings using diffusion-weighted whole-body magnetic resonance imaging with background suppression

European Journal of Radiology Open, 2018
Diffusion-weighted whole-body magnetic resonance imaging with background suppression (DWIBS) is increasingly used in cancer imaging. However, little is known about its usefulness in the management of metastatic seminoma, in which evaluation of the ...
Hideki Takeshita, Satoru Kawakami, Taro Takahara, Kojiro Tachibana, Shunsuke Hiranuma, Hironori Sugiyama, Makoto Kagawa, Akihiro Yano, Yohei Okada, Makoto Morozumi   +9 more
doaj   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source

Diagnostic performance of the microRNA‐371a assay in small testicular masses: a real‐world cohort study

BJU International, EarlyView.
Objectives To evaluate the diagnostic performance of the Conformité Européenne [CE]‐certified microRNA‐371a‐3p (miR371a) assay in patients undergoing inguinal exploration for small testicular masses of unknown histology in a real‐world setting. Patients and Methods Between March 2023 and March 2024, 60 patients underwent inguinal exploration for ...
Felix Seelemeyer, David Pfister, Ruben Gößmann, Olivia Steenbock, Roberto Pappesch, Sabine Merkelbach‐Bruse, Axel Heidenreich   +6 more
wiley   +1 more source

Deep Learning for Subtypes Identification of Pure Seminoma of the Testis

Clinical Pathology
The most critical step in the clinical diagnosis workflow is the pathological evaluation of each tumor sample. Deep learning is a powerful approach that is widely used to enhance diagnostic accuracy and streamline the diagnosis process.
Kirill E Medvedev, Paul H Acosta, Liwei Jia, Nick V Grishin   +3 more
doaj   +1 more source