Results 51 to 60 of about 24,482 (261)

Clinical presentation, management and follow-up of 83 patients with Leydig cell tumors of the testis: a prospective case-cohort study [PDF]

open access: yes, 2019
LCTs are more frequent than generally believed, are associated with male infertility, cryptorchidism and gynecomastia, and should be treated conservatively (in compliant patients) with active surveillance, which appears to be a safe alternative to ...
Cantisani, Vito   +12 more
core   +1 more source

Defining the cellular origin of seminoma by transcriptional and epigenetic mapping to the normal human germline

open access: yesCell Reports
Summary: Aberrant male germline development can lead to the formation of seminoma, a testicular germ cell tumor. Seminomas are biologically similar to primordial germ cells (PGCs) and many bear an isochromosome 12p [i(12p)] with two additional copies of ...
Keren Cheng   +14 more
doaj   +1 more source

Morphological and immunohistochemical characterisation of seminomas in Norwegian dogs

open access: yesActa Veterinaria Scandinavica, 2012
Background Seminomas in the dog have traditionally been assumed to resemble human spermatocytic seminomas, based on their low malignancy and high occurrence in old individuals.
Thorvaldsen Tor   +3 more
doaj   +1 more source

Testicular seminoma presenting as a large conglomerate mass in abdomen

open access: yesRadiology Case Reports
Testicular seminoma commonly occurs in young men aged between 15 and 45 years old. Those with testicular cancer may present with a lump or swelling in the testicle.
Sajanakan Sriselvakumar, MBBS, MoT   +1 more
doaj   +1 more source

Downregulation of Clusterin Expression in Human Testicular Seminoma

open access: yesCellular Physiology and Biochemistry, 2013
Background: Clusterin, a heterodimeric glycoprotein of approximately 80 kDa, exists extensively in human body fluids. The abnormal expression of clusterin is closely related to the occurrence, progression, and prognosis of tumors.
Bianjiang Liu   +9 more
doaj   +1 more source

Management of germ cell tumors in children: Approaches to cure [PDF]

open access: yes, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Calaminus, G.   +4 more
core   +1 more source

Spermatocytic Seminoma

open access: yesArchives of Pathology & Laboratory Medicine, 2009
Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
openaire   +2 more sources

Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? While several nongenetic risk factors are linked to testicular germ‐cell tumors (TGCTs), the influence of environmental and hormonal factors remains unclear. This study evaluated the role of postnatal exposures in the etiology of TGCT using data from the ongoing EPSAM case–control investigation in Italy.
Mauro Cioffi   +10 more
wiley   +1 more source

Bilateral synchronous spermatocytic seminoma: a rare case report from rural India and literature review

open access: yesThe Pan African Medical Journal, 2012
Spermatocytic Seminoma is an unusual germ cell tumour known to arise from testis only. It is associated with good prognosis. Testicular tumours as such are uncommon in Asia as compared to western countries.
Sanjay N Koppad   +4 more
doaj   +1 more source

The treatment of stage A testicular seminoma by carboplatin monochemotherapy [PDF]

open access: yes, 2009
Background/Aim. Although radiotherapy is considered to be a standard treatment of stage A testicular seminoma, an increasing number of studies have reported encouraging results of the treatment by carboplatin monochemotherapy (CBDCA).
Bojanić Nebojša   +4 more
core   +1 more source

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