Results 41 to 50 of about 9,904 (152)
Andrology, EarlyView.ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino +5 more
wiley +1 more source
Protein Expression of PTTG-1, OCT-4, and KLF-4 in Seminoma: A Pilot Study
Frontiers in Endocrinology, 2019 Seminomas are the most frequent kind of testicular germ cell tumors (TGCTs), accounting for 50% of tumor diagnosis in young men, whereas non-seminomas account for 40% and mixed forms for 10% of cases. It is currently supposed that TGCTs evolve from a pre-
Giuseppe Grande +11 more
doaj +1 more source
A 28-Year-Old Man With Mediastinal Seminoma Treated With BEP
Folia Medica Indonesiana, 2021 Highlight: • A 28-year-old male suffered chylothorax and mediastinal seminoma. • The patient received bleomycin, etoposide and cisplatin chemotherapy for the management of mediastinal seminomas but he died beforeundergoing 5th cycle chemotherapy ...
Agustinus Rizki, Laksmi Wulandari
doaj +1 more source
A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer
Andrology, EarlyView.ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner +7 more
wiley +1 more source
BMC Urology, 2006 Background The route of local and metastatic spread of testicular seminoma is well recognised and accepted. The spread is via lymphatics to the paraaortic nodes.
Stubington Simon R +2 more
doaj +1 more source
Asian Journal of Andrology, 2020 Testicular cancer seminoma is one of the most common types of cancer among men of reproductive age. Patients with this condition usually present reduced semen quality, even before initiating cancer therapy.
Tânia R Dias +4 more
doaj +1 more source
Andrology, EarlyView.ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam +7 more
wiley +1 more source
Unusual renal and colonic mass: Description of a rare case
Indian Journal of Medical and Paediatric Oncology, 2019 Seminoma is a germ cell tumor which accounts for approximately 40% of all germ cell tumors. Testicular seminoma is usually localized to the testis, and in 25% of cases, lymph node metastasis is seen. However, rarely, it can metastasize to visceras.
Manika Khare +3 more
doaj +1 more source
A successful in vitro fertilization outcome in a hermaphrodite male
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 424-425, April 2025.
Shima Elbakhit M. E. Albasha +2 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec +18 more
wiley +1 more source