Results 51 to 60 of about 14,996 (221)
PTTG1/ZEB1 Axis Regulates E-Cadherin Expression in Human Seminoma
Simple Summary Seminoma represents one of the most common neoplasms in Caucasian males between 15 and 40 years old. The molecular pathways underlying its clinical behavior are far from being understood yet.
Pontecorvi A. +37 more
core +2 more sources
Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal +8 more
wiley +1 more source
An ultrastructural description of a previously described spontaneous seminoma in a Koi carp (Cyprinus carpio) is given in this note. The seminoma, diagnosed as classical with a diffuse pattern by histology and immunohistochemistry, displayed a ...
G. Vitellozzi +8 more
core +2 more sources
BRD9 inhibition as potential treatment option for testicular germ cell tumors
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen +5 more
wiley +1 more source
Seminoma primário do mediastino [PDF]
O seminoma primário de mediastino é uma neoplasia rara, principalmente em mulheres, nas quais existem apenas oito casos descritos de seminoma. Tem sua maior incidência entre a terceira e quarta décadas, caracterizando-se por grande radiossensibilidade ...
Cesar Giovani Conte +11 more
core +1 more source
Abstract Background Poor semen quality is a well‐known feature in patients with testicular germ cell tumours (GCTs) at the time of diagnosis but the underlying biological reasons are incompletely understood. Objectives This study aimed to identify GCT‐specific clinical factors that are involved with poor semen quality in GCT patients.
Klaus‐Peter Dieckmann +9 more
wiley +1 more source
Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby +10 more
wiley +1 more source
Pure Seminoma Subtyping Using Computational Approaches [PDF]
Testicular germ cell tumors (TGCT) being the most common solid malignancy in adolescent and young men, are second in terms of the average life years lost per person dying of cancer. Two major types of TGCTs are seminoma and non-seminoma (NSE). Management
Medvedev, Kirill E. +4 more
core +1 more source
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Peter A. Kanetsky +28 more
wiley +1 more source
Two cases of spermatocytic seminoma [PDF]
Two cases of spermatocytic seminoma are reported. The first case was a 58-year-old man who visited our hospital with a complaint of painless swollen left scrotal content. Left orchiectomy was performed under the diagnosis of testicular tumor.
加藤, 次朗 +3 more
core

