PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation. [PDF]
, 2018 Germ cell tumors (GCTs) are a heterogeneous group of tumors occurring in gonadal and extragonadal locations. GCTs are hypothesized to arise from primordial germ cells (PGCs), which fail to differentiate.
Chen, Di +4 more
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Androgen receptor polymorphisms and testicular cancer risk [PDF]
, 2015 Testicular cancer (TC) is currently the most common malignant solid tumour in Caucasian males aged 15-39 years. Epidemiological evidence suggests that its onset may be due to an imbalance in the action of steroidal sex hormones and their receptors.
CARLINI, TANIA +9 more
core +1 more source
A population-based case-control study on social factors and risk of testicular germ cell tumours [PDF]
, 2013 Objectives Incidence rates for testicular cancer have risen over the last few decades. Findings of an association between the risk of testicular cancer and social factors are controversial. The association of testicular cancer and different indicators of
Ahrens, W. +8 more
core +1 more source
Seminoma in a gray brocket deer (Mazama gouazoubira) with unilateral cryptorchidism
Brazilian Journal of Veterinary Pathology, 2022 Cryptorchidism is the incomplete descent of the testes and associated structures, and cryptorchid testes are more likely to develop testicular neoplasms, such as seminoma.
Ayisa Rodrigues Oliveira +9 more
doaj +1 more source
A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells. [PDF]
, 2015 Correct orientation of the mitotic spindle in stem cells underlies organogenesis. Spindle abnormalities correlate with cancer progression in germ line-derived tumors.
Bucko, Paula +8 more
core +1 more source
Seminoma in a Man with Russell-Silver Syndrome Presenting with Testicular Torsion
Case Reports in Urology, 2016 Russell-Silver syndrome (RSS) is a type of primordial dwarfism. Only one case of testicular cancer in RSS has been reported, the pathology of which was nonseminoma.
Satoshi Funada +3 more
doaj +1 more source
Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]
, 2000 Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core +1 more source
Primary seminoma of prostate in a patient with Klinefelter syndrome
Medicine, 2022 . Rationale:. Klinefelter syndrome (KS) is a sex differentiation syndrome that occurs in men and is characterized by the 47XXY genotype. An association between KS and cancer has also been reported. The occurrence of seminoma of the prostate in KS has not
Duncheng Shi, MD +6 more
doaj +1 more source
Pan-urologic cancer genomic subtypes that transcend tissue of origin [PDF]
, 2017 Urologic cancers include cancers of the bladder, kidney, prostate, and testes, with common molecular features spanning different types. Here, we show that 1954 urologic cancers can be classified into nine major genomic subtypes, on the basis of ...
Bossé, Dominick +9 more
core +2 more sources
Types of testicular tumors in Shahid Beheshti Hospital of Babol, Iran, during 2001‒2021 [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریزBackground. Testicular tumors account for about 1% of all male cancers. Considering that there is no accurate information about the prevalence of testicular tumors in Iran, this study aimed to investigate the types of testicular tumors in the hospitals ...
Sorena Samimi +2 more
doaj +1 more source