Results 11 to 20 of about 14,996 (221)

5-YEAR RELATIVE SURVIVAL RATE BETWEEN SEMINOMA AND NON-SEMINOMA TESTICULAR CANCER IN SINGLE CENTER [PDF]

Jurnal Urologi Indonesia, 2023
Objective: This study was conducted to provide data about the survival rate of testicular cancer patients with different histology in the year 2013 – 2017 in Adam Malik General Hospital and to compare these estimates with other studies conducted in ...
Ben Julian Mantiri, Ginanda Putra Siregar, Syah Mirsya Warli   +2 more
doaj   +2 more sources

In vivo and FACS-based CRISPR/Cas9 screening uncovers VENTX as a crucial element in maintaining seminoma stemness [PDF]

Translational Oncology
Seminoma, which is the most frequent testicular germ cell tumor, has stem cell-like features related to treatment resistance and recurrence, yet the molecular mechanisms that preserve its stemness are not well understood. This study aimed to discover the
Chaoxiong Huang, Yiran Chen, Enhuan Zhang, Yifan Wang, Yixuan Liu, Lirui Tang, Chuanben Chen, Peicheng Lin, Bingyi Wang   +8 more
doaj   +2 more sources

Late recurrence of Seminoma in the pelvis: A case report

Urology Case Reports, 2021
Recurrence of pure seminoma in atypical lymph node sites, such as the pelvis are rare masses that show clinical signs late in disease progression. We report a case of a 73-year-old male that presented with urinary retention and pain in his left lower ...
Seth Swinney, Allen Medway, Luis Brandi, Pranav Sharma   +3 more
doaj   +2 more sources

Metachronous solitary metastasis from left testicle seminoma presenting as a large intracranial tumor 4 years post-treatment: a case report and review of the literature [PDF]

Journal of Medical Case Reports
Background Seminoma is a highly curable testicular tumor, but metastatic spread to the central nervous system (CNS) is uncommon, and isolated CNS relapse is exceptionally rare.
William Borghol, Ahed Assaf, Suleiman Khaddour, Saja Karaja, Mousa Barboura, Nourta Barboura, Ahmad Chaar, Ahmad Zahi AlChawwaf   +7 more
doaj   +2 more sources

Effective analysis of testicular seminoma toxicity and mechanisms of acetyl tributyl citrate using network toxicology, bulk RNA sequencing data, single-cell RNA sequencing data, and clinical data [PDF]

Frontiers in Immunology
IntroductionAcetyl tributyl citrate (ATBC) is a widely used plasticizer ubiquitously present in the environment. Long-term high-dose ATBC exposure has been associated with reproductive system damage, yet its toxic effects and underlying mechanisms in ...
Haisheng Yi, Haisheng Yi, Yibo Gong, Yibo Gong, Wenjie Yang, Wenjie Yang, Yinzhao Jia, Yinzhao Jia, Jintao Chen, Jintao Chen, Chao Zhang, Chao Zhang, Xueming Lin, Xueming Lin, Hua Tian, Hua Tian, Bo Wu, Bo Wu, Xiaoming Cao, Xiaoming Cao, Gang Liang, Gang Liang, Xiaobin Yuan, Xiaobin Yuan   +23 more
doaj   +2 more sources

Retroperitoneal Seminoma [PDF]

Ca-A Cancer Journal for Clinicians, 1982
E E Smith
exaly   +3 more sources

Semen quality from patients affected by seminomatous and non-seminomatous testicular tumor [PDF]

International Brazilian Journal of Urology, 2021
Testicular cancer is considered a rare disease affecting approximately 1% to 2% of the male population. This neoplasm has a cure rate of over 95%; as a result, a major concern is the future of fertility of carriers from this disease.
Rosana Xavier, Renata Cristina de Carvalho, Renato Fraietta   +2 more
doaj   +1 more source

Hypothesis: when is a seminoma not a seminoma? [PDF]

Journal of Clinical Pathology, 1981
A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid ...
D, Raghavan, E, Heyderman, P, Monaghan, J, Gibbs, E, Ruoslahti, M J, Peckham, A M, Neville   +6 more
openaire   +5 more sources

Clinico-epidemiological Profile and Outcome of Testicular Germ Cell Tumors: A Retrospective Study from a Tertiary Cancer Centre of North-East India

Asian Pacific Journal of Cancer Care, 2023
Introduction: Testicular Germ Cell Tumor (GCT) is a disease of young adults and is also highly curable. But in India, most of the patients present in an advanced stage and succumb to the disease as compared to the Western nations where patients present ...
Amritjot Singh Randhawa, Manas Dubey, Partha Sarathi Roy, Munlima Hazarika, Duncan Khanikar   +4 more
doaj   +1 more source

Higher LSD1 in Non-Seminomatous Germ Cell Tumors and LSD1 Inhibition by NCL1 Suppresses Embryonal Carcinoma Growth. [PDF]

Cancer Sci
LSD1 expression was higher in non‐seminomatous than in seminomatous testicular germ cell tumor components. In embryonal carcinoma models, selective LSD1 inhibition by NCL1 induced epigenetic and apoptotic responses, reduced viability including in cisplatin‐adapted cells, and suppressed early xenograft outgrowth, supporting LSD1 as a potential ...
Shimizu N, Etani T, Naiki T, Naiki-Ito A, Sugiyama Y, Nagai T, Murakami A, Kato H, Morikawa T, Aoki M, Gonda M, Suzuki H, Tsubouchi Y, Ishikawa D, Suzuki T, Takahashi S, Yasui T.   +16 more
europepmc   +2 more sources