Results 11 to 20 of about 9,904 (152)

Clinicopathological Features, Treatment Patterns, and Long-Term Survival in Patients With Testicular Cancer: A Retrospective Cohort Study. [PDF]

Cancer Rep (Hoboken)
ABSTRACT Background Testicular cancer represents the most common solid tumor in young adult males and is associated with excellent long‐term survival outcomes. Aim The aim of this study is to evaluate clinical and pathological characteristics, treatment strategies, and survival outcomes of a large Romanian institutional cohort.
Rohozneanu EF, Deac C, Căinap CI.
europepmc   +2 more sources

A Rare Case of Seminoma in an Elderly Patient With Suspected Lynch Syndrome. [PDF]

Clin Case Rep
ABSTRACT Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer, is caused by mutations in the mismatch repair genes and confers genetic predisposition to colorectal and other cancers. Germ cell tumors, the majority of which are seminomas, usually arise sporadically and predominantly occur in younger patients; their association ...
Kamandi M, Boozari M, Soltani E, Soltani S.   +3 more
europepmc   +2 more sources

Baseline characteristics and patterns of care in testicular cancer patients: first data from the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS)

Swiss Medical Weekly, 2018
BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments.
Christian Rothermundt, Claudio Thurneysen, Richard Cathomas, Beat Müller, Walter Mingrone, Anita Hirschi-Blickenstorfer, Tobias Wehrhahn, Christian Ruf, Sacha I. Rothschild, Bettina Seifert, Angelika Terbuch, Thomas Grassmugg, Regina Woelky, Christian Fankhauser, Thomas Kunit, Natalie Fischer, Roman Inauen, Katrin Ziegler, Alan Haynes, Peter Jüni, Jeanine Kehl, Silke Gillessen   +21 more
doaj   +1 more source

Three-gene prognostic biomarkers for seminoma identified by weighted gene co-expression network analysis.

PLoS ONE, 2020
Testicular germ cell tumors (TGCTs) are common in young males, and seminoma accounts for a large proportion of TGCTs. However, there are limited records on the exploration of novel biomarkers for seminoma.
Hualin Chen, Gang Chen, Yang Pan, Xiaoxiang Jin   +3 more
doaj   +1 more source

Giant seminoma case with very small yolk sac and embryo carcinoma components, detected by intensive histopathological examination

Human Pathology: Case Reports, 2016
We experienced the giant seminoma with 18 × 10 × 10 cm sized and about 2.6 kg weight of 25 year old patient. We intensively examined the histological tissue type distributions in this giant seminoma. Most of the tumor consisted of seminoma components. In
Takeo Nakaya, MD, Shuichiro Kobayashi, MD, Satoshi Kitahara, MD, Akira Tanaka, MD, Hiroshi Kamma, MD, Akio Komatsu, MD   +5 more
doaj   +1 more source

Clusterin suppresses invasion and metastasis of testicular seminoma by upregulating COL15a1

Molecular Therapy: Nucleic Acids, 2021
Seminoma is the most common subtype of testicular germ cell tumor, with an increasing incidence worldwide. Clusterin (CLU) expression was found to be downregulated in testicular seminoma in our previous study. We now expanded the sample size, and further
Yankang Cui, Chenkui Miao, Shouyong Liu, Jingyuan Tang, Jing Zhang, Hengtao Bu, Yuhao Wang, Chao Liang, Meiling Bao, Chao Hou, Jiajin Wu, Xiaochao Chen, Xiang Zhang, Zengjun Wang, Bianjiang Liu   +14 more
doaj   +1 more source

Integrated Molecular Analysis Reveals 2 Distinct Subtypes of Pure Seminoma of the Testis

Cancer Informatics, 2022
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in adolescent and young men, with a rising incidence over the past 20 years.
Kirill E Medvedev, Anna V Savelyeva, Kenneth S Chen, Aditya Bagrodia, Liwei Jia, Nick V Grishin   +5 more
doaj   +1 more source

Two decades of FDG-PET/CT in seminoma: exploring its role in diagnosis, surveillance and follow-up

Cancer Imaging, 2022
Background Survivors of testicular cancer may experience long-term morbidity following treatment. There is an unmet need to investigate techniques that can differentiate individuals who need additional therapy from those who do not.
Ciara Conduit, Thuan Tzen Koh, Michael S Hofman, Guy C Toner, Jeremy Goad, Nathan Lawrentschuk, Keen-Hun Tai, Jeremy H Lewin, Ben Tran   +8 more
doaj   +1 more source

Características clínico-oncológicas y sobrevida global de pacientes con tumor testicular de células germinales registrados en el hospital militar central “CRL Luis Arias Schreiber” en el periodo del 2004 al 2014

Revista de la Facultad de Medicina Humana, 2018
Objetivo: Identificar las características clínico oncológicas y sobrevida global en pacientes con tumor testicular de células germinales seminoma y no seminoma.
Robert Malpartida Palomino, Rómulo Cárdenas-Agramonte   +1 more
doaj   +3 more sources

Seminoma in a gray brocket deer (Mazama gouazoubira) with unilateral cryptorchidism

Brazilian Journal of Veterinary Pathology, 2022
Cryptorchidism is the incomplete descent of the testes and associated structures, and cryptorchid testes are more likely to develop testicular neoplasms, such as seminoma.
Ayisa Rodrigues Oliveira, Daniel Oliveira dos Santos, Fernanda M. A. M. Pereira, Thaynara Parente de Carvalho, Izabela Magalhães Arthuso Vasconcelos, Lucas dos Reis de Souza, Laice Alves da Silva, Ana Beatriz Portes Gonçalves, Lauro L. S. Neto, Renato Lima Santos   +9 more
doaj   +1 more source