Results 21 to 30 of about 14,416 (223)

Hypothesis: when is a seminoma not a seminoma? [PDF]

Journal of Clinical Pathology, 1981
A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid ...
D, Raghavan, E, Heyderman, P, Monaghan, J, Gibbs, E, Ruoslahti, M J, Peckham, A M, Neville   +6 more
openaire   +5 more sources

Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment

Nature Communications, 2023
Seminoma is the most common malignant solid tumor in 14 to 44 year-old men. However, its molecular features and tumor microenvironment (TME) is largely unexplored.
Xiaojian Lu, Yanwei Luo, Xichen Nie, Bailing Zhang, Xiaoyan Wang, Ran Li, Guangmin Liu, Qianyin Zhou, Zhizhong Liu, Liqing Fan, James M. Hotaling, Zhe Zhang, Hao Bo, Jingtao Guo   +13 more
doaj   +1 more source

CHARACTERISTIC CHEMOTHERAPY RESPONSE OF TESTICULAR CANCER PATIENTS IN TERTIARY HOSPITAL

Jurnal Urologi Indonesia, 2022
Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution.
Dio Mafazi Fabrianta, Kurnia Penta Seputra, Besut Daryanto   +2 more
doaj   +1 more source

CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β

Acta Biochimica et Biophysica Sinica, 2022
Testicular seminoma is a relatively rare tumor which is mostly detected in male population aged from 15 to 35 years old. Although several molecular biomarkers have been identified to be associated with testicular seminoma pathogenesis, the exact ...
Cao Yuming, Chen Zhenlie, Qin Zihan, Qian Kaiyu, Liu Tongzu, Zhang Yuanzhen   +5 more
doaj   +1 more source

Thymic seminoma [PDF]

Indian Journal of Medical and Paediatric Oncology, 2009
AbstractThymic seminoma is a rare clinical entity. We report a case of an 18-year-old male patient who presented with chest pain, dyspnea, dysphagia of 1-month duration. Contrast-enhanced computer tomogram of chest showed an anterior mediastinal mass. He was subjected to thoracotomy and excision of the mass. Histopathology examination revealed seminoma
Kannan, J., Karkuzhali, P., Lakshminarasimhan, S.   +2 more
openaire   +2 more sources

Single-Cell RNA Sequencing of Metastatic Testicular Seminoma Reveals the Cellular and Molecular Characteristics of Metastatic Cell Lineage

Frontiers in Oncology, 2022
BackgroundTesticular cancer is the most common solid malignancy in young men. Given the many histological classifications of testicular tumors, seminoma is one of the most treatable cancers.
Linjian Mo, Linjian Mo, Zhenyuan Yu, Zhenyuan Yu, Yufang Lv, Yufang Lv, Jiwen Cheng, Haibiao Yan, Wenhao Lu, Wenhao Lu, Cheng Su, Cheng Su, Qiang Ling, Qiang Ling, Zengnan Mo, Zengnan Mo   +15 more
doaj   +1 more source

Anaplastic seminoma [PDF]

Cancer, 1977
Eight patients with the diagnosis of anaplastic seminoma of the testicle were treated during the megavoltage era from January 1959 to January 1976. Two patients with Stage I disease and one patient with Stage IV disease have died from their malignancy.
M, Kademian, A, Bosch, W L, Caldwell, W, Jaeschke   +3 more
openaire   +2 more sources

Testis-Sparing Surgery for Metachronous Testicular Tumor Following Orchiectomy. [PDF]

IJU Case Rep
ABSTRACT Introduction For metachronous bilateral testicular tumors occurring in young adulthood, the post‐treatment quality of life must be considered when making treatment decisions. Case Presentation A 46‐year‐old man presented to our hospital with a chief complaint of two bean‐sized hard masses palpable in the right testis.
Tobiume M, Nishikawa G, Aoki S, Morinaga S, Yamada Y, Yamada E, Buma Y, Ogawa H, Nakane S, Yamada Y.   +9 more
europepmc   +2 more sources

Baseline characteristics and patterns of care in testicular cancer patients: first data from the Swiss Austrian German Testicular Cancer Cohort Study (SAG TCCS)

Swiss Medical Weekly, 2018
BACKGROUND The majority of germ cell tumour (GCT) patients can be cured by orchiectomy followed by active surveillance or subsequent systemic and/or local treatments.
Christian Rothermundt, Claudio Thurneysen, Richard Cathomas, Beat Müller, Walter Mingrone, Anita Hirschi-Blickenstorfer, Tobias Wehrhahn, Christian Ruf, Sacha I. Rothschild, Bettina Seifert, Angelika Terbuch, Thomas Grassmugg, Regina Woelky, Christian Fankhauser, Thomas Kunit, Natalie Fischer, Roman Inauen, Katrin Ziegler, Alan Haynes, Peter Jüni, Jeanine Kehl, Silke Gillessen   +21 more
doaj   +1 more source

Three-gene prognostic biomarkers for seminoma identified by weighted gene co-expression network analysis.

PLoS ONE, 2020
Testicular germ cell tumors (TGCTs) are common in young males, and seminoma accounts for a large proportion of TGCTs. However, there are limited records on the exploration of novel biomarkers for seminoma.
Hualin Chen, Gang Chen, Yang Pan, Xiaoxiang Jin   +3 more
doaj   +1 more source