Results 51 to 60 of about 31,992 (113)

Cellular Senescence and Immunosenescence in Melanoma: Insights From the Tumor Microenvironment

Cancer Medicine
Background Melanoma is one of the most immunogenic malignancies, yet resistance to immune checkpoint inhibitors (ICIs) remains a major obstacle to durable therapeutic success.
Lihua Xiong, Jian Cheng
doaj   +1 more source

Senescence-associated secretory phenotype: the "pathogenic" factor driving orthopedic degenerative diseases and its regulation. [PDF]

Front Aging
Ren J, Wang X, Zhou X, Fan X.
europepmc   +1 more source

Inflammaging and Senescence-Associated Secretory Phenotype (SASP) in Psoriasis - A Narrative Review of Potential Mechanisms and Anti-Inflammaging Strategies. [PDF]

Psoriasis (Auckl)
Filipek K, Nowowiejska-Purpurowicz J, Flisiak I.   +2 more
europepmc   +1 more source

Transcriptomic Insights into the Association of IL-1 Signaling with the Senescence-Associated Secretory Phenotype in Human Fibroblasts. [PDF]

Genes (Basel)
Yilmaz V.
europepmc   +1 more source

Impairment of Macrophage Functions by the Senescence-Associated Secretory Phenotype of Vascular Smooth Muscle Cells-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Tsitsipatis D, Rodriguez Rivera T, Kaileh M, Okereke AN, Gupta A, Singh A, Raph SM, Henry-Smith C, Herman AB.   +8 more
europepmc   +1 more source

Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging. [PDF]

Nat Aging
Hao X, Zhao B, Yan Q, Yano M, Matsuoka A, Qi Y, Liao L, Zielinski RJ, Tang HY, Kossenkov AV, Zal MA, Sarma K, Zhang R.   +12 more
europepmc   +1 more source

Resolvin D1 attenuates senescence-associated secretory phenotype independently of TGF-β-driven cardiac fibroblasts differentiation to myofibroblast. [PDF]

J Inflamm (Lond)
Román M, Osorio JM, Espinoza-Pérez C, Machuca V, Peiró C, Ferrer CS, Vivar R, Díaz-Araya G.   +7 more
europepmc   +1 more source

Iron overload triggers pathological remodeling of corneal stroma through ferroptosis and senescence-associated secretory phenotype in keratoconus. [PDF]

Redox Biol
Liu X, Dou S, Wei C, Liu T, Zhang X, Zhang L, Zhao L, Li W, Bao Q, Gao H.   +9 more
europepmc   +1 more source

A spatiotemporal atlas of senescence-associated secretory phenotype in fracture healing: stage-dependent mechanisms and therapeutic windows. [PDF]

Inflamm Regen
Chen B, Li G, Fang Q, Ding P, Gao Y.
europepmc   +1 more source

Subclonal β-catenin/YAP signaling heterogeneity accelerates ovarian cancer metastasis through a senescence-associated secretory phenotype. [PDF]

Cell Death Dis
To SKY, Yang Y, Shi Z, Fung KSW, Lai SL, Li JJX, Ip PPC, Wong AST.   +7 more
europepmc   +1 more source