Status of sennosides content in various Indian herbal formulations: Method standardization by HPTLC [PDF]
Bangladesh Journal of Pharmacology, 2008 Several poly-herbal formulations containing senna (Cassia angustifolia) leaves are available in the Indian market for the treatment of constipation.
Md. Wasim Aktar +2 more
doaj +6 more sources
Promotion of intestinal peristalsis by Bifidobacterium spp. capable of hydrolysing sennosides in mice. [PDF]
PLoS ONE, 2012 BACKGROUND:While there are a variety of identifiable causes of constipation, even idiopathic constipation has different possible mechanisms. Sennosides, the main laxative constituents of Daio, an ancient Kampo medicine, are prodrugs that are converted to
Mitsuharu Matsumoto +5 more
doaj +3 more sources
Essai de culture du Cassia italica au Burkina Faso : evolution des teneurs en sennosides au cours de la croissance [PDF]
Tropicultura, 1985 Cultivation attempt of Cassia italica in Burkina Faso : sennosides content evolution during plant development. This paper presents the basic principles for an exploitation of cassia italica in the sennosides production (medicinal use : laxatives).
Dame, C. +5 more
doaj +2 more sources
Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.), a Non-Model Plant with Potent Laxative Properties. [PDF]
PLoS ONE, 2015 Senna (Cassia angustifolia Vahl.) is a world's natural laxative medicinal plant. Laxative properties are due to sennosides (anthraquinone glycosides) natural products.
Nagaraja Reddy Rama Reddy +6 more
doaj +2 more sources
Analysis of sennoside in drugs contained senna leaves (Cassia sp.) in Iran [PDF]
Research Journal of Pharmacognosy, 2017 Background and objectives: The importance of Cassia angustifulia is due to its laxative properties. A large number of sennosides have been reported in senna but sennoside A and B have been reported as the main causes of its properties.
M. Tayefeh +4 more
doaj +2 more sources
Development of a validated HPLC method for the determination of sennoside A and B, two major constituents of Cassia obovata Coll. [PDF]
Journal of HerbMed Pharmacology, 2014 Introduction: Cassia obovata Coll is the only Senna species which grows wild in Iran. In the present study, an optimised reverse High Performance Liquid Chromatography (HPLC) validated method was established for quantification of sennosides A and B, the ...
Ghassemi-Dehkordi Nasrollah +2 more
doaj +5 more sources
Is Senna Laxative Use Associated to Cathartic Colon, Genotoxicity, or Carcinogenicity? [PDF]
Journal of Toxicology, 2009 Due to their natural origin, apparent low oral toxicity, effectiveness, and accessibility without a medical prescription, the anthranoid laxatives are a popular remedy for constipation and are frequently used abusively.
M. A. Morales +4 more
doaj +2 more sources
Outcomes Following Constipation Treatments Between Parkinson's Disease and Non-Parkinson's Disease Patients Evaluated by the Constipation Scoring System. [PDF]
Parkinsons DisObjectives The Constipation Scoring System (CSS) is a validated tool for assessing constipation severity and has been previously applied in Parkinson’s disease (PD) populations. However, comparative data on post‐treatment CSS outcomes between individuals with and without PD remain lacking.
Methawasin K +4 more
europepmc +2 more sources
A Case of Methemoglobinemia Suspected to Be Induced by Rabeprazole. [PDF]
Acute Med SurgRabeprazole‐induced methemoglobinemia was observed in an elderly woman, resolving after discontinuation and recurring on reintroduction. Other causes were excluded. To our knowledge, this is the first reported case suggesting proton pump inhibitors may cause methemoglobinemia, and prompt withdrawal is essential. ABSTRACT Background Methemoglobinemia is
Kawasaki R +9 more
europepmc +2 more sources
Laxative-induced contact burns from accidental ingestion of senna in a 2-year-old female. [PDF]
JPGN RepAbstract Senna (sennosides) is a natural stimulant laxative containing anthraquinone glycosides, commonly used to treat constipation. We present the case of a healthy 2‐year‐old female (~12.5 kg) who is not yet toilet‐trained and accidentally ingested a single 15 mg chocolate‐flavored sennoside chew (1.2 mg/kg). This led to sharply demarcated erythema,
Olorunsogo T, Oarhe CO, Miri AR.
europepmc +2 more sources