Results 111 to 120 of about 2,191,303 (292)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Design of Divided Condensers for Desiccant Wheel-Assisted Separate Sensible and Latent Cooling AC Systems [PDF]
, 2012 A desiccant wheel-assisted separate sensible and latent cooling air-conditioning system improves the energy efficiency of conventional air-conditioning systems by increasing the evaporating temperature of the refrigerant for sensible cooling.
Radermacher, Reinhard +2 more
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Sensible Heat Flux in Near-Neutral Conditions over the Sea [PDF]
The variation of the sea surface sensible heat flux is investigated using data from the Gulf of Tehuantepec Experiment (GOTEX) and from eight additional aircraft datasets representing a variety of surface conditions. This analysis focuses on near-neutral
Khelif, Djamal +3 more
core +4 more sources
Roles of forests in moderating the diurnal cycle of land–atmosphere interactions
Environmental Research LettersForests moderate the microclimate through evapotranspiration and biomass heat flux. However, understanding the contributions of dense forests remains challenging due to observational limitations.
Yi-Shin Jang +4 more
doaj +1 more source
The annual surface energy budget of a high-arctic permafrost site on Svalbard, Norway [PDF]
The Cryosphere, 2009 Independent measurements of radiation, sensible and latent heat fluxes and the ground heat flux are used to describe the annual cycle of the surface energy budget at a high-arctic permafrost site on Svalbard.
S. Westermann +4 more
doaj
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley +1 more source