Results 81 to 90 of about 1,009,466 (301)

Radio Recombination Lines at Decametre Wavelengths: Prospects for the Future

, 2010
This paper considers the suitability of a number of emerging and future instruments for the study of radio recombination lines (RRLs) at frequencies below 200 MHz. These lines arise only in low-density regions of the ionized interstellar medium, and they
Anantharamaiah, Blake, Bridle, de Oliveira-Costa, Ellingson, Erickson, Furlanetto, Furlanetto, Golynkin, Golynkin, Harker, Helmboldt, Kantharia, Kantharia, Konovalenko, Konovalenko, Lidz, N. E. Kassim, Payne, Payne, Pritchard, Stepkin, T. E. Clarke, T. J. W. Lazio, W. C. Erickson, W. M. Peters   +25 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Estimating Economic Regional Effects of Euro 2012: Ex-ante and Ex-post Approach

Management and Business Administration. Central Europe, 2014
Purpose: In this paper we evaluate both ex-ante and ex-post macroeconomic impact of EURO 2012TM on Polish regions. Methodology: We start with modifying the Keynesian-style multiplier model to investigate the effects of Euro 2012-related spending on ...
Barbara Despiney, Waldemar Karpa
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Spatial Clustering of High Redshift Lyman Break Galaxies

, 2012
We present a physically motivated semi-analytic model to understand the clustering of high redshift LBGs. We show that the model parameters constrained by the observed luminosity function, can be used to predict large scale (\theta > 80 arcsec) bias and ...
Adelberger, Adelberger, Benson, Benson, Berlind, Berlind, Berrier, Best, Bielby, Bouwens, Bouwens, Bouwens, Bower, Bromm, Bullock, Bullock, Bullock, Charles Jose, Chiu, Choudhury, Conroy, Cooray, Cooray, Dijkstra, Giavalisco, González, González, González, Hamana, Hamana, Hildebrandt, Iliev, Jing, Jose, Kandaswamy Subramanian, Kashikawa, Khochfar, Kravtsov, Labbé, Larson, Lee, Lee, Lee, Leitherer, Madau, Mo, More, Navarro, Oke, Ouchi, Ouchi, Peebles, Porciani, Prada, Raghunathan Srianand, Reddy, Reddy, Samui, Samui, Samui, Samui, Samui, Saumyadip Samui, Savoy, Scannapieco, Scoccimarro, Seljak, Sheth, Sheth, Skibba, Somerville, Somerville, Springel, Stark, Stark, Steidel, Steidel, Tinker, van den Bosch, van der Burg, Wilkins, Yang, Zehavi, Zehavi, Zehavi, Zheng, Zheng   +86 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Development of the Marketing Strategy of Mediahost.sk on the Czech Market [PDF]

, 2012
Diplomová práca sa zameriava na vývoj marketingovej stratégie firmy Mediahost.sk na slovenskom trhu. Analyzuje makro a mikro prostredie v IT priemysle, a to najmä so zameraním na webhosting.
Kapičák, Tomáš
core  

Direct Evidence of an Eruptive, Filament-Hosting Magnetic Flux Rope Leading to a Fast Solar Coronal Mass Ejection

, 2014
Magnetic flux ropes (MFRs) are believed to be at the heart of solar coronal mass ejections (CMEs). A well-known example is the prominence cavity in the low corona that sometimes makes up a three-part white-light (WL) CME upon its eruption. Such a system,
Bastian, Timothy S., Chen, Bin, Gary, Dale E.   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source