Results 21 to 30 of about 10,610 (187)
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Impact Analysis of Hull Line Design on Fishing Vessels’ Vulnerability to Pure Loss of Stability
Journal of Marine Science and EngineeringPure Loss of Stability is one of the five typical stability failure modes identified in the Second-Generation Intact Stability Criteria by the IMO. This study investigates the influence of hull line variations on the vulnerability of a saury fishing ...
Hangming Zhang +4 more
doaj +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
MathematicsInjection molding is widely used for plastic parts, but its performance is limited by the cooling stage, which dominates cycle time and affects dimensional stability and energy consumption.
Carlos Pereira +2 more
doaj +1 more source
, 2013 This paper proposed an transient-based optimal parametric tuning method for power system stabilizer (PSS) based on trajectory sensitivity (TS) analysis of hybrid system, such as hybrid power system (HPS). The main objective is to explore a systematic optimization approach of PSS under large disturbance of HPS, where its nonlinear features cannot be ...
openaire +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
MathematicsThis paper develops a mathematical approach to the analysis of the stability of economic equilibria in nonsmooth models. The λ-Hölder apparatus of subdifferentials is used, which extends the class of systems under study beyond traditional smooth ...
Anna V. Aleshina +3 more
doaj +1 more source
UNCERTAIN MODEL OF REACTOR IN PROCESS OF PRODUCTION GREASE ON SOAP THICKENERS
Вісник Національного технічного університету України «Київський політехнічний інститут імені Ігоря Сікорського»: Серія «Хімічна інженерія, екологія та ресурсозбереження», 2017 In this article consider the problem of guaranteed quality controlled processes with uncertain parameters of the functional components of management, set interval or fuzzy way.
Антон Петрович Коротинський +1 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source