Results 31 to 40 of about 98,745 (247)

Stability of closed-loop fractional-order systems and definition of damping contours for the design of controllers [PDF]

open access: yes, 2012
Fractional complex order integrator has been used since 1991 for the design of robust control-systems. In the CRONE control methodology, it permits the parameterization of open loop transfer function which is optimized in a robustness context.
Lanusse, Patrick   +2 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Robust H8 design for resonant control in a CVCF inverter application over load uncertainties [PDF]

open access: yes, 2020
CVCF (constant voltage, constant frequency) inverters are electronic devices used to supply AC loads from DC storage elements such as batteries or photovoltaic cells. These devices are used to feed different kinds of loads; this uncertainty requires that
Bueno Contreras, Holman   +2 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Machine learning-driven building energy optimization: integrating EnsembleXGBoost sensitivity analysis with meta-heuristic algorithms and carbon economics

open access: yesEnergy Conversion and Management: X
While recent building optimization studies achieve significant energy reductions, they often overlook two critical gaps: (1) proceeding on fixed, non-optimized building geometries, and (2) using machine learning (ML) solely as computational surrogates ...
Mahdi Asghari   +2 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Impact Analysis of Hull Line Design on Fishing Vessels’ Vulnerability to Pure Loss of Stability

open access: yesJournal of Marine Science and Engineering
Pure Loss of Stability is one of the five typical stability failure modes identified in the Second-Generation Intact Stability Criteria by the IMO. This study investigates the influence of hull line variations on the vulnerability of a saury fishing ...
Hangming Zhang   +4 more
doaj   +1 more source

On the Selection of Tuning Methodology of FOPID Controllers for the Control of Higher Order Processes [PDF]

open access: yes, 2012
In this paper, a comparative study is done on the time and frequency domain tuning strategies for fractional order (FO) PID controllers to handle higher order processes. A new fractional order template for reduced parameter modeling of stable minimum/non-
Alomoush   +56 more
core   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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