Results 41 to 50 of about 12,461 (219)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Mechanistic and optimization based analysis of bio inspired multiscale flow fields for water management in PEM fuel cells

International Journal of Electrochemical Science
This work presents a mechanistic and optimization-based analysis of bio-inspired multiscale flow-fields for water management and performance enhancement in proton exchange membrane fuel cells (PEMFCs).
Ala’a Al-Falahat, Saad S. Alrwashdeh
doaj   +1 more source

UNCERTAIN MODEL OF REACTOR IN PROCESS OF PRODUCTION GREASE ON SOAP THICKENERS

Вісник Національного технічного університету України «Київський політехнічний інститут імені Ігоря Сікорського»: Серія «Хімічна інженерія, екологія та ресурсозбереження», 2017
In this article consider the problem of guaranteed quality controlled processes with uncertain parameters of the functional components of management, set interval or fuzzy way.
Антон Петрович Коротинський, Михайло Володимирович Коржик   +1 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Behavior of steel columns with double curvature: a numerical simulation and design-oriented parametric study

Fracture and Structural Integrity
This research present a novel investigation, which focuses on the numerical exploration of steel columns having a double curvature, built with both hollow square and circular cross-sections.
Hamda Guedaoura, Mohammed Benzerara, Nadia Gouider, Yazid Hadidane, Anfel Chaima Hadidane   +4 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Power Transformer Vibration Analysis Model Based on Ensemble Learning Algorithm

IEEE Access
The inflow of DC magnetic flux into the core of power transformers under DC bias conditions leads to a significant increase in operational losses, noise levels, and vibration amplitudes, posing substantial threats to the stability and reliability of the ...
Baidi Shi, Yongfeng Jiang, Wei Xiao, Jingyu Shang, Meng Li, Zixing Li, Xinfu Chen   +6 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Design and Multiphysics Modeling of Robust SWCNT/NiO Core–Shell Hole Transport Layers in All‐Perovskite Tandem Solar Cells

Advanced Energy & Sustainability Research
This study employs advanced 3D opto‐electro‐thermal (OET) simulations based on the finite element method to analyze and optimize perovskite tandem solar cells (TSC) featuring CsPbI3/MASnI3 active layers.
Javad Maleki, Ali Akbar Haji Zeynali Biyoki, Maryam Shahrostami, Mehrshad Masoudi, Mohammad Bagher Mohammadzadeh Shamloo, Kosar Mohammadi   +5 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source