Results 41 to 50 of about 12,439 (217)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Mechanistic and optimization based analysis of bio inspired multiscale flow fields for water management in PEM fuel cells

International Journal of Electrochemical Science
This work presents a mechanistic and optimization-based analysis of bio-inspired multiscale flow-fields for water management and performance enhancement in proton exchange membrane fuel cells (PEMFCs).
Ala’a Al-Falahat, Saad S. Alrwashdeh
doaj   +1 more source

UNCERTAIN MODEL OF REACTOR IN PROCESS OF PRODUCTION GREASE ON SOAP THICKENERS

Вісник Національного технічного університету України «Київський політехнічний інститут імені Ігоря Сікорського»: Серія «Хімічна інженерія, екологія та ресурсозбереження», 2017
In this article consider the problem of guaranteed quality controlled processes with uncertain parameters of the functional components of management, set interval or fuzzy way.
Антон Петрович Коротинський, Михайло Володимирович Коржик   +1 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Behavior of steel columns with double curvature: a numerical simulation and design-oriented parametric study

Fracture and Structural Integrity
This research present a novel investigation, which focuses on the numerical exploration of steel columns having a double curvature, built with both hollow square and circular cross-sections.
Hamda Guedaoura, Mohammed Benzerara, Nadia Gouider, Yazid Hadidane, Anfel Chaima Hadidane   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Power Transformer Vibration Analysis Model Based on Ensemble Learning Algorithm

IEEE Access
The inflow of DC magnetic flux into the core of power transformers under DC bias conditions leads to a significant increase in operational losses, noise levels, and vibration amplitudes, posing substantial threats to the stability and reliability of the ...
Baidi Shi, Yongfeng Jiang, Wei Xiao, Jingyu Shang, Meng Li, Zixing Li, Xinfu Chen   +6 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Design and Multiphysics Modeling of Robust SWCNT/NiO Core–Shell Hole Transport Layers in All‐Perovskite Tandem Solar Cells

Advanced Energy & Sustainability Research
This study employs advanced 3D opto‐electro‐thermal (OET) simulations based on the finite element method to analyze and optimize perovskite tandem solar cells (TSC) featuring CsPbI3/MASnI3 active layers.
Javad Maleki, Ali Akbar Haji Zeynali Biyoki, Maryam Shahrostami, Mehrshad Masoudi, Mohammad Bagher Mohammadzadeh Shamloo, Kosar Mohammadi   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source