Results 41 to 50 of about 98,745 (247)

Data-Driven Multi-Objective Optimization of Conformal Cooling Channels for Energy-Efficient Injection Molding

Mathematics
Injection molding is widely used for plastic parts, but its performance is limited by the cooling stage, which dominates cycle time and affects dimensional stability and energy consumption.
Carlos Pereira, António J. Pontes, António Gaspar-Cunha   +2 more
doaj   +1 more source

Auto-generation of passive scalable macromodels for microwave components using scattered sequential sampling [PDF]

, 2014
This paper presents a method for automatic construction of stable and passive scalable macromodels for parameterized frequency responses. The method requires very little prior knowledge to build the scalable macromodels thereby considerably reducing the ...
Chemmangat Manakkal Cheriya, Krishnan, Dhaene, Tom, Knockaert, Luc   +2 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Solving ill-posed bilevel programs [PDF]

, 2016
This paper deals with ill-posed bilevel programs, i.e., problems admitting multiple lower-level solutions for some upper-level parameters. Many publications have been devoted to the standard optimistic case of this problem, where the difficulty is ...
AG Mersha, AG Mersha, B Colson, BS Mordukhovich, BS Mordukhovich, BS Mordukhovich, BS Mordukhovich, BS Mordukhovich, DA Molodtsov, G-H Lin, H Bonnel, HF von Stackelberg, J Fliege, J Jahn, J-P Aubin, JF Bard, JJ Ye, JJ Ye, JJ Ye, JJ Ye, JV Outrata, M Xu, M Červinka, NQ Huy, P Loridan, R Lucchetti, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dempe, S Dias, S Ruuska, SM Robinson, TXD Ha, W Wiesemann   +43 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Analysis of λ-Hölder Stability of Economic Equilibria and Dynamical Systems with Nonsmooth Structures

Mathematics
This paper develops a mathematical approach to the analysis of the stability of economic equilibria in nonsmooth models. The λ-Hölder apparatus of subdifferentials is used, which extends the class of systems under study beyond traditional smooth ...
Anna V. Aleshina, Andrey L. Bulgakov, Yanliang Xin, Igor Y. Panarin   +3 more
doaj   +1 more source

Marginal Likelihood Estimation with the Cross-Entropy Method [PDF]

, 2012
We consider an adaptive importance sampling approach to estimating the marginal likelihood, a quantity that is fundamental in Bayesian model comparison and Bayesian model averaging.
Chan, Joshua, Eisenstat, Eric
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Dynamic Characteristic of a Faulted Rotor System with Multi-Objective Optimization Designed SFD

Applied Sciences, 2019
As an important part of the turbomachinery, the rotor–bearing system has been upgraded to provide a high rotating speed in order to meet the demand of high power production.
Liang Ma, Jun Wang, Guichang Zhang
doaj   +1 more source

Thermal Control of a Dual Mode Parametric Sapphire Transducer

, 2009
We propose a method to control the thermal stability of a sapphire dielectric transducer made with two dielectric disks separated by a thin gap and resonating in the whispering gallery (WG) modes of the electromagnetic field. The simultaneous measurement
Belfi, Jacopo, Beverini, Nicolò, De Michele, Andrea, Gabbriellini, Gianluca, Mango, Francesco, Passaquieti, Roberto   +5 more
core   +1 more source