Results 101 to 110 of about 3,543,475 (319)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Efficient Cataluminescence Sensor for Detecting Methanol Based on NiCo2O4//MIL-Ti125 Polyhedral Composite Nano-Materials

open access: yesChemosensors
Since methanol has a significant health hazard due to its inherent toxicity, it is urgent to develop a method capable of rapid, sensitive, and continuous monitoring of methanol.
Hongyan Wang   +4 more
doaj   +1 more source

Sensitivity [PDF]

open access: yesThe Primary Care Companion For CNS Disorders, 2006
openaire   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Sensitive and Selective Electrochemical Detection of Hydrogen Peroxide Using a Silver-Incorporated CeO2/Ag2O Nanocomposite

open access: yesBiosensors
Precision and real-time detection of hydrogen peroxide (H2O2) are essential in pharmaceutical, industrial, and defence sectors due to its strong oxidizing nature.
Gunasekaran Manibalan   +4 more
doaj   +1 more source

Sensitivity to PRIMA-1MET is associated with decreased MGMT in human glioblastoma cells and glioblastoma stem cells irrespective of p53 status

open access: diamond, 2016
Mariia Patyka   +5 more
openalex   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Designing Novel MEMS Cantilevers for Marine Sensing Robots Using COMSOL Modeling and Different Piezoelectric Materials

open access: yesEngineering Proceedings
The present work presents an innovative marine sensing robotics device based on piezoelectric cantilever-integrated micro-electro-mechanical systems (MEMSs) modeled on fish lateral lines.
Basit Abdul   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy