Results 61 to 70 of about 2,651,129 (312)
Sensitivity analysis and parameter estimation for evaluating the impact of water pollution on aquatic species [PDF]
Computational Ecology and SoftwareAquatic ecosystems are highly sensitive to changes in environmental conditions, making it essential to identify the key factors that influence the dynamics of species populations.
Christopher David Ngalya +2 more
doaj
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii +8 more
wiley +1 more source
Pygpc: A sensitivity and uncertainty analysis toolbox for Python
SoftwareX, 2020 We present a novel Python package for the uncertainty and sensitivity analysis of computational models. The mathematical background is based on the non-intrusive generalized polynomial chaos method allowing one to treat the investigated models as black ...
Konstantin Weise +4 more
doaj +1 more source
Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes
FEBS Letters, EarlyView.The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji +3 more
wiley +1 more source
Mitochondrial fatty acid oxidation is stimulated by red light irradiation
FEBS Letters, EarlyView.Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera +4 more
wiley +1 more source
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1
FEBS Letters, EarlyView.Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji +5 more
wiley +1 more source
Clinical Epidemiology, 2013 Chenglin Ye,1,2 Gina Browne,1,3 Joseph Beyene,1 Lehana Thabane1,2 1Department of Clinical Epidemiology and Biostatistics, McMaster University, 2Biostatistcs Unit, St Joseph's Healthcare Hamilton, 3School of Nursing, McMaster University, Hamilton, ON,
Ye C, Browne G, Beyene J, Thabane L
doaj
Sensitivity and uncertainty analysis
, 2023 This NEXOGENESIS Deliverable describes the methodological approaches to be employed within the System Dynamics Models (SDMs) for each of the five Case Studiesregarding: scenario analysis; sensitivity analysis; what-if testing; and uncertainty analysis. It outlines why these methods are essential for improved policy-relevant information.
Janez Sušnik +5 more
openaire +1 more source