Results 81 to 90 of about 2,651,129 (312)

Sensitivity Analysis in OLAP Databases

open access: yesProceedings of the 20th International Conference on Enterprise Information Systems, 2018
The theoretical underpinnings under which sensitivity analysis is valid in OLAP databases are dealt with in this paper. Sensitivity analysis is considered to be the reverse of explanation generation in diagnostic reasoning. Our exposition differentiates between sensitivity analysis in systems of purely drill-down equation and mixed systems of equations
Hennie Daniels, Emiel Caron
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Sensitivity analysis and uncertainty quantification of stiffness modulus using indirect tensile test

open access: yesInternational Journal of Applied Mechanics and Engineering
The stiffness modulus is a critical element in pavement engineering, as its accurate measurement directly reflects the load-bearing capacity of the pavement section.
Hicham Mezouara   +4 more
doaj   +1 more source

Climate variability from annual to multi-decadal timescales in a two-layer stochastic energy balance model: analytic solutions and implications for general circulation models

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2019
A low-order stochastically forced two-layer global energy balance model (EBM) admitting an analytical solution is developed for studying natural inter-annual, decadal and multi-decadal climate variability, and ultimately to better understand forced ...
Sergei Soldatenko, Robert Colman
doaj   +1 more source

Sensitivity Analysis of BLISK Airfoil Wear †

open access: yesInternational Journal of Turbomachinery, Propulsion and Power, 2018
The decreasing performance of jet engines during operation is a major concern for airlines and maintenance companies. Among other effects, the erosion of high-pressure compressor (HPC) blades is a critical one and leads to a changed aerodynamic behavior,
Andreas Kellersmann   +2 more
doaj   +1 more source

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