MRI and MRA Sensitivity and Specificity for Accurate Diagnosis of Labral Tear for Patients Undergoing Hip Arthroscopy With Concomitant Periacetabular Osteotomy. [PDF]
Zhang Y +4 more
europepmc +1 more source
SENSITIVITY AND SPECIFICITY OF PROSTATIC BIOPSY RESULT BASED ON PROSTATE VOLUME
Joko Pitoyo, Ferry Safriadi
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Reliability of Frozen Section Biopsy in Detecting Endometrial Pathologies: A Systematic Review of Sensitivity and Specificity. [PDF]
Ali Mohammed MA +5 more
europepmc +1 more source
Effect of varying sensitivity and specificity of the nLRDT for Scenario 1 and Scenario 2.
Aren Sargood (22513356) +3 more
openalex +1 more source
TREX1, a predator for treating MSI‐H tumors?
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Sensitivity and specificity of the neutrophil-to-lymphocyte ratio for predicting mortality in patients with non-metastatic acral melanoma. [PDF]
Pallares CNC +5 more
europepmc +1 more source

