Results 181 to 190 of about 2,595,666 (406)

Production of Potent Anti-Australia Antigen Sera of High Specificity and Sensitivity in Goats

, 1972
Gordon R. Dreesman, F. Blaine Hollinger, Robert M. McCombs, Joseph L. Melnick   +3 more
openalex   +1 more source

Recognition by cytotoxic T lymphocytes of Qa-2 antigens. Sensitivity of Qa-2 molecules to phosphatidylinositol-specific phospholipase C. [PDF]

, 1988
Donald W. Mann, James Forman
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Determination of Total Urinary Protein, Combining Lowry Sensitivity and Biuret Specificity

, 1973
K Doetsch, Richard H. Gadsden
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Perioperative Myocardial Infarction Associated with Coronary Artery Bypass Graft Surgery: Improved Sensitivity in the Diagnosis Within 6 Hours after Operation with 99mTc-Glucoheptonate Myocardial Imaging and Myocardial-Specific Isoenzymes

, 1979
Arthur J. Roberts, John Combes, Jerome G. Jacobstein, Daniel R. Alonso, Martin R. Post, Valavanur A. Subramanian, Ronald M. Abel, Norman Brachfeld, Susan A. Kline, William A. Gay   +9 more
openalex   +1 more source

Screening Urine Specimen Populations for Normality Using Different Dipsticks: Evaluation of Parameters Influencing Sensitivity and Specificity [PDF]

, 1987
Christine M.C. Bank, John Codrington, Marja P. van Dieijen‐Visser, P. J. Brombacher   +3 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Shortened questionnaires to assess anxiety and depression during in-hospital rehabilitation: clinical validation and cutoff scores

Neuropsychiatric Disease and Treatment, 2016
Giorgio Bertolotti,1 Loretta Moroni,1 Roberto Burro,2 Antonio Spanevello,3 Roberto FE Pedretti,4 Giandomenico Giorgetti5 1Psychology Unit, Salvatore Maugeri Foundation, IRCCS, Scientific Institute, Tradate, 2Department of Human Sciences &ndash ...
Bertolotti G, Moroni L, Burro R, Spanevello A, Pedretti RFE, Giorgetti G   +5 more
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