Results 221 to 230 of about 1,766,628 (360)

Class-agnostic annotation of small RNAs balances sensitivity and specificity in diverse organisms. [PDF]

Comput Struct Biotechnol J
Johnson NR, Gonzalez-Toro F, Gomez BB.
europepmc   +1 more source

Statistics Notes: Diagnostic tests 1: sensitivity and specificity

British medical journal, 1994
D. G. Altman, J. Bland
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Methodological choices strongly modulate the sensitivity and specificity of lesion-symptom mapping analyses

Moore MJ, Rorden C, Robinson GA, Mattingley JB, Demeyere N.   +4 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Sensitivity and Specificity of Natural Language Processing Systems for Identification of Hospitalized People Who Use Drugs. [PDF]

Open Forum Infect Dis
Benrubi L, Sato T, Westgard LK, Zollo-Venecek K, Socrates B, Sweigart B, Ridgway JP, Suzuki J, Morales Y, Goodman-Meza D, Wurcel AG.   +10 more
europepmc   +1 more source

High-Sensitivity Detection of Invasive Ductal Carcinoma via Domain-Specific SimCLR Pre-Training [PDF]

Mufakir Qamar Ansari
openalex   +1 more source

Sensitivity and Specificity of Diffusion-Weighted Magnetic Resonance Imaging in Diagnosis of Bladder Cancers.

Clinical and investigative medicine. Medecine clinique et experimentale, 2015
N. Zhai, Yan-Hui Wang, Lai-Ming Zhu, Jie-huan Wang, Xin-hai Sun, Xi-bin Hu, Xian Li, Tao Yu, Xin-ling Wang, Nan Meng, Qi-chang Yan, Xuejiao Li, Yahong Luo   +12 more
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Brief Diagnostic Criteria for Temporomandibular Disorders: Sensitivity and Specificity of Clinical Diagnoses (A Multi-Center Study). [PDF]

J Oral Rehabil
Nykänen L, Sipilä K, Eli I, Freidman-Rubin P, Keren L, Kämppi A, Näpänkangas R, Tamar SA, Tanner J, Teerijoki-Oksa T, Winocur E, Emodi-Perlman A.   +11 more
europepmc   +1 more source