Results 51 to 60 of about 4,475,159 (380)

Determination of a cutoff for noise sensitivity: Psychometric evaluation of the Turkish Noise Sensitivity Questionnaire (Tr-NoiSeQ)

Noise and Health, 2022
Context: There is a need for a clear cutoff to use noise sensitivity (NS) scale as a prediagnostic tool in research and clinical use. Aims: Noise sensitivity questionnaire (NoiSeQ) was adapted into Turkish language (Tr-NoiSeQ); validity and reliability ...
Asuman Alniacik, Eda Çakmak
doaj   +1 more source

Textual analysis of clinical notes on pathology request forms to determine sensitivity and specificity of Hepatitis B and C virus infection status [PDF]

arXiv, 2022
Background: It is not established whether clinical notes provided on pathology request forms are useful as decision support data when assessing Hepatitis B and C viral infection status. Objective: To determine sensitivity, specificity, and predictive value of clinical notes for identifying infection status of Hepatitis B and C.
arxiv  

Evaluation of delirium screening tools in geriatric medical inpatients: a diagnostic test accuracy study [PDF]

, 2016
Introduction: screening all unscheduled older adults for delirium is recommended in national guidelines, but there is no consensus on how to perform initial assessment.
Burns, Jennifer, Cunnington, AnneLouise, Evans, Jonathan, Hendry, Kirsty, Miller, Hazel, Quinn, Terence J., Scortichini, Valeria, Stott, David J.   +7 more
core   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Sensitivity and Specificity of Photoaptamer Probes [PDF]

Molecular & Cellular Proteomics, 2003
The potential of photoaptamers as proteomic probes was investigated. Photoaptamers are defined as aptamers that bear photocross-linking functionality, in this report, 5-bromo-2'-deoxyuridine. A key question regarding the use of photoaptamer probes is the specificity of the cross-linking reaction.
Brian D. Collins, Tad H. Koch, James Heil, Drew Smith   +3 more
openaire   +3 more sources

Using the VALGENT-3 framework to assess the clinical and analytical performance of the RIATOL qPCR HPV genotyping assay [PDF]

, 2019
Background and objective: The VALGENT framework is developed to assess the clinical performance of HPV tests that offer genotyping capability. Samples from the VALGENT-3 panel are used to identify an optimal viral concentration threshold for the RIATOL ...
Arbyn, Marc, Benoy, I, Bogers, Johannes, Poljak, M., Valencak, A. Ostrbenk, Vanden Broeck, Davy, Xu, Lan   +6 more
core   +1 more source

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

FEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr, Klaus Mayer, Raffael Schaffrath, Johannes Buchner, Ulrich Brinkmann   +4 more
wiley   +1 more source

Diagnostic Value of Lactoferrin in Diagnosis of Urinary Tract Infections in Children

مجله دانشکده پزشکی اصفهان, 2018
Background: Urinary tract infections is a common disease, especially in children, and is diagnosed through urine culture. The aim of this study was to evaluate the diagnostic value of lactoferrin in the diagnosis of urinary tract infections. Methods: In
Alireza Merrikhi, Zahra Parsapour
doaj   +1 more source

Factors Associated with Marburg Hemorrhagic Fever: [PDF]

, 2010
Background. Reliable on-site polymerase chain reaction (PCR) testing for Marburg hemorrhagic fever (MHF) is not always available. Therefore, clinicians triage patients on the basis of presenting symptoms and contact history.
Bengi Moco Henrique, Benjamin Jeffs, Fernando Paixao Damiao Machado, Heinz Feldmann, James E. Strong, Luis Villa, Matthias Borchert, Oscar Bernal, Pascoal Nascimento Folo, Pedro Pablo Palma, Roddy, Paul, Sara L Thomas, Steven M. Jones   +12 more
core   +2 more sources

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source