Results 61 to 70 of about 4,361,080 (379)

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

FEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang, Meritxell Wu‐Lu, Alberto Collauto, Peter‐Leon Hagedoorn, Madalina Alexandru, Maike Henschel, Shahram Kordasti, Maria Andrea Mroginski, Maxie M. Roessler, Kourosh H. Ebrahimi   +9 more
wiley   +1 more source

A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma [PDF]

, 2017
Aims: CDX2 is widely used as a sensitive and specific immunomarker for colorectal carcinoma (CRC) but neither this sensitivity nor specificity is absolute. This study is the first known comparison of CDX1 and A33 against CDX2 as immunomarkers for CRC.
Adamczyk, Lukasz A., Cullen, Jayne, Evans, Shanna, Oien, Karin A., Oniscu, Anca, Wong, Newton A.C.S.   +5 more
core   +1 more source

Sensitivity and specificity of median nerve ultrasonography in diagnosis of carpal tunnel syndrome

International Journal of General Medicine, 2012
Mohammad Yazdchi1, Mohammad Kazem Tarzemani2, Haleh Mikaeili3, Hormoz Ayromlu1, Hooman Ebadi11Neuroscience Research Center, 2Department of Radiology, 3Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz ...
Yazdchi M, Tarzemani MK, Mikaeili H, Ayromlu H, Ebadi H   +4 more
doaj  

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

High-sensitivity cardiac troponin T and copeptin assays to improve diagnostic accuracy of exercise stress test in patients with suspected coronary artery disease [PDF]

, 2014
Background: The average diagnostic sensitivity of exercise stress tests (ESTs) is lower than that of other non-invasive cardiac stress tests. The aim of the study was to examine whether high-sensitivity cardiac troponin T (hs-cTnT) or copeptin ...
Dörr, Oliver, Gaede, Luise, Hamm, Christian W., Hoffmann, Jedrzej, Liebetrau, Christoph, Möllmann, Helge, Nef, Holger M., Rolf, Andreas, Weber, Michael, Wolter, Jan S.   +9 more
core   +1 more source

Sensitivity and specificity of the iVue iWellnessExam™ in detecting retinal and optic nerve disorders

Eye and Brain, 2013
Catherine Awad,1 Samantha Slotnick,2,3 Sanjeev Nath,4 Jerome Sherman2–41Nova Southeastern College of Optometry, Fort Lauderdale-Davie, FL, 2SUNY State College of Optometry, 3SUNY Eye Institute, 4Eye Institute and Laser Center, New York, NY ...
Awad C, Slotnick S, Nath S, Sherman J
doaj  

Physical Examination of the Ankle: A Review of the Original Orthopedic Special Test Description and Scientific Validity of Common Tests for Ankle Examination

Archives of Rehabilitation Research and Clinical Translation, 2020
Objectives: To review the literature, identify and describe commonly used special tests for diagnosing injury to the ligaments of the ankle complex, present the distinguishing characteristics and limitations of each test, and discuss the current evidence
Lindsay W. Larkins, DAT, Russell T. Baker, PhD, DAT, Jayme G. Baker, DPT   +2 more
doaj  

Sensitivity curves for spaceborne gravitational wave interferometers [PDF]

Phys.Rev.D62:062001,2000, 1999
To determine whether particular sources of gravitational radiation will be detectable by a specific gravitational wave detector, it is necessary to know the sensitivity limits of the instrument. These instrumental sensitivities are often depicted (after averaging over source position and polarization) by graphing the minimal values of the gravitational
arxiv   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

Factors Associated with Marburg Hemorrhagic Fever: [PDF]

, 2010
Background. Reliable on-site polymerase chain reaction (PCR) testing for Marburg hemorrhagic fever (MHF) is not always available. Therefore, clinicians triage patients on the basis of presenting symptoms and contact history.
Bengi Moco Henrique, Benjamin Jeffs, Fernando Paixao Damiao Machado, Heinz Feldmann, James E. Strong, Luis Villa, Matthias Borchert, Oscar Bernal, Pascoal Nascimento Folo, Pedro Pablo Palma, Roddy, Paul, Sara L Thomas, Steven M. Jones   +12 more
core   +2 more sources