Results 101 to 110 of about 899,236 (314)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

FINDING DEFECTS IN AUTOMATIC CONTROL SYSTEMS BASED ON STRUCTURE SENSITIVITY FUNCTIONS AND ANALYSIS OF INTEGRAL ESTIMATES OF OUTPUT SIGNALS

, 2021
Sergey V. Shalobanov, S.S. Shalobanov, A. A. Aleksandrov   +2 more
openalex   +1 more source

Automatic control systems: optimization and sensitivity study [PDF]

, 2020
Л. А. Денисова, R D Karabtsov, V A Meshcheryakov, I. V. Shirokov   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Oscillation energy based sensitivity analysis and control for multi-mode\n oscillation systems [PDF]

, 2017
Horacio Silva-Saravia, Yajun Wang, Héctor Pulgar-Painemal, Kevin Tomsovic   +3 more
openalex   +1 more source

Risk-sensitive control of cash management systems

Operational Research, 2017
[EN] Firms manage cash for operational, precautionary and speculative purposes. Stat-of-the-art cash management models usually focus on cost minimization by means of a set of controlling bounds. In this paper, we propose a multiobjective model to control cash management systems with multiple accounts characterized by generalized cash flow processes. In
openaire   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Discrete Centralized AGC Using LQR-Based Cost Functional Minimization for Multi-Area Interconnected Power Systems

IEEE Access
This paper proposes the design of Discrete Centralized Optimal Quadratic Automatic Generation Control (COQAGC) based on the functional minimization method (FMM) and optimal control theory for interconnected power systems. The cost function and FMM design
Mohammed Esmail, Senthil Krishnamurthy
doaj   +1 more source

Controlling arrival and service rates to reduce sensitivity of queueing systems with customer abandonment [PDF]

, 2021
Katsunobu Sasanuma, Robert C. Hampshire, Alan Scheller‐Wolf   +2 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source