Results 51 to 60 of about 5,977,029 (374)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Efficient Data Transmission Using MPPM Dimming Control in Indoor Visible Light Communication

IEEE Photonics Journal, 2015
In conventional visible light communication (VLC) dimming control systems utilizing pulse width modulation (PWM), reducing the duty cycle will push up the receiver sensitivity requirement if the transmission rate is kept constant.
Xiaodi You, Jian Chen, Huanhuan Zheng, Changyuan Yu   +3 more
doaj   +1 more source

Evaluating Reactivity Control Options for a Chloride Salt-Based Molten Salt Zero-Power Reactor

Applied Sciences, 2021
Molten salt reactors have gained substantial interest in recent years due to their flexibility and their potential for simplified closed fuel cycle operation for massive net-zero energy production.
Bruno Merk, Anna Detkina, Seddon Atkinson, Dzianis Litskevich, Gregory Cartland-Glover   +4 more
doaj   +1 more source

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, EarlyView.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

An Easily Understandable Grey Wolf Optimizer and Its Application to Fuzzy Controller Tuning

Algorithms, 2017
This paper proposes an easily understandable Grey Wolf Optimizer (GWO) applied to the optimal tuning of the parameters of Takagi-Sugeno proportional-integral fuzzy controllers (T-S PI-FCs). GWO is employed for solving optimization problems focused on the
Radu-Emil Precup, Radu-Codrut David, Alexandra-Iulia Szedlak-Stinean, Emil M. Petriu, Florin Dragan   +4 more
doaj   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

FEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment

FEBS Letters, EarlyView.
This study explores the distinct molecular mechanisms underlying Lynch syndrome‐associated and sporadic colorectal cancer (CRC). By highlighting the therapeutic potential of targeting the PI3K‐Akt pathway in Lynch syndrome‐associated CRC and the Wnt pathway in sporadic CRC, the findings open avenues for personalised treatment strategies, aiming to ...
May J. Krause, Musalula Sinkala, Raj Ramesar   +2 more
wiley   +1 more source

Expanding biological control to bioelectronics with machine learning

APL Materials, 2020
Bioelectronics integrates electronic devices and biological systems with the ability to monitor and control biological processes. From homeostasis to sensorimotor reflexes, closed-loop control with feedback is a staple of most biological systems and ...
J. Selberg, M. Jafari, C. Bradley, M. Gomez, M. Rolandi   +4 more
doaj   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

IDENTIFICATION OF REFUSALS OF CONTROL SYSTEMS OF AIRCRAFTS BY MEANS OF SENSITIVITY FUNCTIONS

Научный вестник МГТУ ГА, 2016
Article is devoted to detection and identification of refusals of governing bodies like "withdrawal and a klineniye" in ideal statement (the atmosphere - not indignant, sensors - ideal). Relevance of consideration of the matters is caused by a problem of
A. D. Barabash, I. N. Merzlikin
doaj