Results 71 to 80 of about 1,044,965 (267)
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
This is an expository paper that discusses an approach to the linear quadratic Gaussian/loop transfer recovery (LQG/LTR) design problem for finite-dimensional single-variable (single-input/single-output, SISO) control systems.
Mahyar Mahinzaeim, Kamyar Mehran
doaj +1 more source
Optimal Control for One-Qubit Quantum Sensing
Quantum systems can be exquisite sensors thanks to their sensitivity to external perturbations. This same characteristic also makes them fragile to external noise. Quantum control can tackle the challenge of protecting a quantum sensor from environmental
F. Poggiali, P. Cappellaro, N. Fabbri
doaj +1 more source
Optimally sensitive controller for digital systems
A scheme is developed which allows an optimal control policy to be maintained in cases where the parameters of the controlled system deviate by a small amount from the values expected. This is achieved by augmenting the nominally correct controller design to allow updating of the system control vector on the basis of observed deviations from the ideal ...
W.F. Fincham, C.L. Nikias
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Sensitivity of an eigenvalue of a multivariable control system
In determining the sensitivity of response of a linear time-invariant dynamic system, extensive use is made of the concepts of eigenvalue and eigenvector sensitivity. In an earlier paper, a closed-form expression for the eigenvalue-sensitivity coefficient was obtained.
openaire +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Control of delay systems for minimax sensitivity.
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 1986 ; Vita. ; Bibliography: leaves 161-162. ; by David S. Flamm. ; Ph. D. ; Ph. D.
openaire +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source

