Results 71 to 80 of about 1,044,965 (267)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

An approach to the LQG/LTR design problem with specifications for finite-dimensional SISO control systems

open access: yesSystems Science & Control Engineering
This is an expository paper that discusses an approach to the linear quadratic Gaussian/loop transfer recovery (LQG/LTR) design problem for finite-dimensional single-variable (single-input/single-output, SISO) control systems.
Mahyar Mahinzaeim, Kamyar Mehran
doaj   +1 more source

Optimal Control for One-Qubit Quantum Sensing

open access: yesPhysical Review X, 2018
Quantum systems can be exquisite sensors thanks to their sensitivity to external perturbations. This same characteristic also makes them fragile to external noise. Quantum control can tackle the challenge of protecting a quantum sensor from environmental
F. Poggiali, P. Cappellaro, N. Fabbri
doaj   +1 more source

Optimally sensitive controller for digital systems

open access: yesElectronics Letters, 1979
A scheme is developed which allows an optimal control policy to be maintained in cases where the parameters of the controlled system deviate by a small amount from the values expected. This is achieved by augmenting the nominally correct controller design to allow updating of the system control vector on the basis of observed deviations from the ideal ...
W.F. Fincham, C.L. Nikias
openaire   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Sensitivity of an eigenvalue of a multivariable control system

open access: yesElectronics Letters, 1966
In determining the sensitivity of response of a linear time-invariant dynamic system, extensive use is made of the concepts of eigenvalue and eigenvector sensitivity. In an earlier paper, a closed-form expression for the eigenvalue-sensitivity coefficient was obtained.
openaire   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Control of delay systems for minimax sensitivity.

open access: yes, 1986
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 1986 ; Vita. ; Bibliography: leaves 161-162. ; by David S. Flamm. ; Ph. D. ; Ph. D.
openaire   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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