Results 51 to 60 of about 2,233,236 (246)
The impact of FASTQ and alignment read order on structural variant calling from long-read sequencing data [PDF]
PeerJBackground Structural variant (SV) calling from DNA sequencing data has been challenging due to several factors, including the ambiguity of short-read alignments, multiple complex SVs in the same genomic region, and the lack of “truth” datasets for ...
Kyle J. Lesack, James D. Wasmuth
doaj +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Robustness in Timed Automata [PDF]
, 2013 In this paper we survey several approaches to the robustness of timed automata, that is, the ability of a system to resist to slight perturbations or errors.
Markey, Nicolas +7 more
core +1 more source
Sensitivity Analysis of Evolutionary Algorithm for Software Reusability
Mendel, 2019 Fast and competitive software industry demands rapid development using Component Based Software Development (CBSD). CBSD is dependent on the availability of the high-quality reusable component libraries.
Amit Rathee, Jitender Kumar Chhabra
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Robust Classification with Context-Sensitive Features
CoRR, 1993 This paper addresses the problem of classifying observations when features are context-sensitive, especially when the testing set involves a context that is different from the training set. The paper begins with a precise definition of the problem, then general strategies are presented for enhancing the performance of classification algorithms on this ...
openaire +4 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
A Weighted Grid for Measuring Program Robustness [PDF]
, 2012 Robustness is a key issue for all the programs, especially safety critical ones. In the literature, Program Robustness is defined as “the degree to which a system or component can function correctly in the presence of invalid input or stressful ...
ABDALLAH, MOHAMMAD,MAHMOUD,AREF
core