Results 71 to 80 of about 2,233,236 (246)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
CHIMIAIt is an enormous challenge to bring chemical sensing concepts from a controlled laboratory setting into the field while maintaining accuracy. In an environment of uncontrolled, fluctuating temperatures and a lack of repeated calibration, sensor ...
Eric Bakker
doaj +1 more source
Malaria Journal, 2019 Background The development of malaria transmission-blocking strategies including the generation of malaria refractory mosquitoes to replace the wild populations through means of gene drives hold great promise.
Tibebu Habtewold +5 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Robustness of animal production systems : concept and application to practical cases [PDF]
, 2011 A concept and method are developed and applied to improve robustness in animal ...
Napel, J., ten, Groot Koerkamp, P.W.G.
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Robustness - a challenge also for the 21st century: A review of robustness phenomena in technical, biological and social systems as well as robust approaches in engineering, computer science, operations research and decision aiding [PDF]
Notions on robustness exist in many facets. They come from different disciplines and reflect different worldviews. Consequently, they contradict each other very often, which makes the term less applicable in a general context.
Hüser, Christian
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Robustness of Energy Delivery and Economic Sensitivity in Onshore and Offshore Wind Power
EnergiesThe increasing penetration of wind generation requires performance evaluation methods that extend beyond average annual energy production. Temporal delivery characteristics, such as monthly dispersion and exposure to low-production periods, can influence
Fernando M. Camilo +2 more
doaj +1 more source
Sensitivity Analysis of Compressive Sensing Solutions
Frontiers in Robotics and AI, 2015 The compressive sensing framework □nds a wide range of applications in signal processing, data analysis and fusion. Within this framework, various methods have been proposed to □nd a sparse solution x from a linear measurement model y = Ax.
Liyi eDai
doaj +1 more source