Results 121 to 130 of about 702,487 (357)

"THE SENSITIVENESS OF THE PERITONEUM." [PDF]

open access: yesThe Lancet, 1893
n ...
Sherrington, C. S., Littlewood, H.
openaire   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Sensitization and its impact on Reproductive and sexual health issues of adolescents in clinics and schools - a comparative study.

open access: yesAsian Journal of Medical Sciences, 2011
Objective: Adolescent Reproductive and Sexual Health Issue is an important component of Youth Friendly Health Services. The objective of this study to compare the impact of sensitization on adolescent reproductive and sexual health issues of adolescent ...
Arun Kumar De
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Sodium hydroxide pretreatment as an effective approach to reduce the dye/holes recombination reaction in P-Type DSCs [PDF]

open access: yes, 2019
We report the synthesis of a novel squaraine dye (VG21-C12) and investigate its behavior as p-type sensitizer for p-type Dye-Sensitized Solar Cells.
Barbero, Nadia   +5 more
core   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Edible Insects and Allergy Risks: Implications for Children and the Elderly

open access: yesAllergies
Population growth and the depletion of natural resources have driven the incorporation of edible insects into the human food matrix. Despite their high nutritional value and the environmental benefits of insect farming compared to conventional protein ...
Alessandra de Cássia Romero
doaj   +1 more source

Habituation to pain : a motivational-ethological perspective [PDF]

open access: yes, 2019
Habituation to pain is mainly studied using external pain stimuli in healthy volunteers, often to identify the underlying brain mechanisms, or to investigate problems in habituation in specific forms of pain (eg, migraine).
Crombez, Geert   +2 more
core   +1 more source

On The Sensitivity Conjecture.

open access: yesElectron. Colloquium Comput. Complex., 2016
The sensitivity of a Boolean function f:{0,1}^n -> {0,1} is the maximal number of neighbors a point in the Boolean hypercube has with different f-value. Roughly speaking, the block sensitivity allows to flip a set of bits (called a block) rather than just one bit, in order to change the value of f. The sensitivity conjecture, posed by Nisan and Szegedy
openaire   +4 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

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