Results 111 to 120 of about 702,487 (357)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Amelioration of cisplatin sensitivity in human cervical cancer: Epigallocatechin-3-Gallate
Frontiers in Nutrition, 2015 Cisplatin is one of the effective chemotherapeutics in the treatment of several types of cancers. However, in addition to the efforts against to its toxicity, the amelioration of cisplatin sensitivity is an important point in treatment of cervical cancer.
Ulkan eKilic +8 more
doaj +1 more source
, 1999 Excerpt: A form of aversion therapy in which a covert response such as a thought or an image is followed by an imagined aversive event. An individual may imagine himself relaxing in front of the television and eating a large bowl of hot buttered popcorn,
Bufford, Rodger K.
core
, 2019 Purpose of Review Chronic rhinosinusitis and nasal polyps (CRSwNP) is a common condition that significantly affects patients' life. This work aims to provide an up-to-date overview of CRSwNP in older adults, focusing on its aging-related clinical ...
Bachert, Claus +3 more
core +2 more sources
Two-center holographic recording [PDF]
, 2001 We describe a two-center holographic recording method for the storage of persistent holograms in doubly doped lithium niobate crystals. We use a two-center model, and we show that our experimental observations can be explained by the model.
Adibi, Ali +2 more
core +1 more source
Annals of Nutrition and Metabolism, 2015 Non-celiac gluten sensitivity (NCGS) is a syndrome characterized by intestinal and extraintestinal symptoms related to the ingestion of gluten-containing food in subjects who are not affected by either celiac disease (CD) or wheat allergy (WA). The prevalence of NCGS is not clearly defined yet.
openaire +2 more sources
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Journal of Neuroscience, 2008 Central sensitization, increased sensitivity in spinal cord dorsal horn neurons after injuries, plays an essential role in the induction and maintenance of chronic pain. However, synaptic mechanisms underlying central sensitization are incompletely known.
Yasuhiko Kawasaki +3 more
semanticscholar +1 more source
Sensitiveness of the Peritoneum [PDF]
The American Journal of the Medical Sciences, 1901 n ...
openaire +2 more sources