Bidirectional Communication of the Gut-Brain Axis in Pain Regulation: From Microbial Metabolites to Neuroinflammation. [PDF]
Song Z +5 more
europepmc +1 more source
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun +7 more
wiley +1 more source
CONTACT SENSITIZATION TO NICKEL FROM RHODIUM-PLATED 'NICKEL-FREE' EARRINGS [PDF]
VENA G.A. +4 more
core
Neuro-sensitization in cats with chronic pain and its association to osteoarthritis progression. [PDF]
Lefort-Holguin M +9 more
europepmc +1 more source
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li +4 more
wiley +1 more source
Animal models of fungus-related allergic airway disease: exposures, readouts, mechanisms, and translational gaps. [PDF]
Qu Y +6 more
europepmc +1 more source
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa +8 more
wiley +1 more source
From vector to allergen: exploring the immunology of tick-triggered α-Gal syndrome. [PDF]
Petry J, Swiontek K, Hilger C.
europepmc +1 more source
Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun +6 more
wiley +1 more source
Paraventricular thalamus hyperactivity mediates stress-induced sensitization of unlearned fear but not stress-enhanced fear learning (SEFL). [PDF]
Nishimura KJ +4 more
europepmc +1 more source

