Results 21 to 30 of about 376,740 (195)

Myricetin Suppresses the Propagation of Hepatocellular Carcinoma via Down-Regulating Expression of YAP

open access: yesCells, 2019
Myricetin is a naturally occurring flavonoid with protective effects against a variety of cancers. However, the molecular mechanism of myricetin against hepatocellular carcinoma (HCC) has still not been fully elucidated.
Minjing Li   +6 more
doaj   +1 more source

Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]

open access: yes, 2018
The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A.   +5 more
core   +2 more sources

Mesocorticolimbic monoamine correlates of methamphetamine sensitization and motivation

open access: yesFrontiers in Systems Neuroscience, 2014
Methamphetamine (MA) is a highly addictive psychomotor stimulant, with life-time prevalence rates of abuse ranging from 5-10% world-wide. Yet, a paucity of research exists regarding MA addiction vulnerability/resiliency and neurobiological mediators of ...
Kevin D Lominac   +13 more
doaj   +1 more source

Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]

open access: yes, 2008
Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins   +47 more
core   +1 more source

Adenovirus-Mediated Sensitization to the Cytotoxic Drugs Docetaxel and Mitoxantrone Is Dependent on Regulatory Domains in the E1ACR1 Gene-Region [PDF]

open access: yes, 2012
Oncolytic adenoviruses have shown promising efficacy in clinical trials targeting prostate cancers that frequently develop resistance to all current therapies.
Daniel Öberg   +7 more
core   +7 more sources

Dynamic Search-Space Pruning Techniques in Path Sensitization [PDF]

open access: yes, 1994
— A powerful combinational path sensitization engine is required for the efficient implementation of tools for test pattern generation, timing analysis, and delay fault testing.
Marques-Silva, Joao, Sakallah, Karem
core   +2 more sources

Evolving Sensitivity [PDF]

open access: yesACS Chemical Biology, 2006
Engineering gene circuits with novel functions holds promise for broad applications in biology, engineering, and medicine. Directed evolution complements rational design as an important strategy for optimizing gene circuits and circuit elements.
Hao, Song, Lingchong, You
openaire   +2 more sources

O comportamento Fotoquímico dos Complexos Pentaaminas de Rutênio(II) com Ligantes π Insaturados The photochemical behaviour of pentaamineruthenium(ii) complexes with unsaturated π ligands

open access: yesQuímica Nova, 1997
A general overview on the photochemical behaviour of [Ru(NH3)5L]2+ complexes (where L is a p ligand) is presented. The proposed mechanisms and techniques employed for the study of these reactions are discussed.
Rose Maria Carlos   +2 more
doaj   +1 more source

Cross-sensitization between poppy seed and buckwheat in a food-allergic patient with poppy seed anaphylaxis [PDF]

open access: yes, 2006
The opium poppy, Papaver somniferum L., is the source of both poppy seeds and opium. The commercially available seeds are widely used as ingredients for various kinds of food.
Oppel, T., Thomas, P., Wollenberg, A.
core   +1 more source

Influence of Age, Host Plant and Mating Status in Pheromone Production and New Insights on Perception Plasticity in Tuta Absoluta

open access: yesInsects, 2019
The tomato leafminer Tuta absoluta Meyrick (Lepidoptera: Gelechiidae) is one of the most important pests of tomato worldwide. However, in spite of its tremendous economic importance, the success of environmentally friendly measures to control the pest is
Aroa Domínguez   +4 more
doaj   +1 more source

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