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To Sensitize or Not to Sensitize [PDF]
Hypertension, 2016 See related article, pp 970–976 Hypertension greatly increases the risk for major causes of disability and death including heart disease, target-organ damage, and stroke.1 The risk for cardiovascular disease is compounded by the high incidence of obesity and insulin resistance in patients with hypertension.
openaire +3 more sources
Frontiers in Pediatrics, 2021 Background and Objectives: Anaphylaxis, a severe allergic disease, can be triggered by various causes. This study investigated the association between allergic sensitization and anaphylactic symptoms and the severity of anaphylaxis in children.Patients ...
Won Seok Lee +3 more
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Metabotropic glutamate receptor 2/3 (mGluR2/3) activation suppresses TRPV1 sensitization in mouse, but not human sensory neurons [PDF]
, 2018 The use of human tissue to validate putative analgesic targets identified in rodents is a promising strategy for improving the historically poor translational record of preclinical pain research.
Baranger, David A.A. +5 more
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Hypofunctional TrkA Accounts for the Absence of Pain Sensitization in the African Naked Mole-Rat
Cell Reports, 2016 The naked mole-rat is a subterranean rodent lacking several pain behaviors found in humans, rats, and mice. For example, nerve growth factor (NGF), an important mediator of pain sensitization, fails to produce thermal hyperalgesia in naked mole-rats. The
Damir Omerbašić +9 more
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Emerging New Approaches in Desensitization: Targeted Therapies for HLA Sensitization
Frontiers in Immunology, 2021 There is an urgent need for therapeutic interventions for desensitization and antibody-mediated rejection (AMR) in sensitized patients with preformed or de novo donor-specific HLA antibodies (DSA).
Ashley Y. Choi +8 more
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Heterologous carriers in the anamnestic antihapten response [PDF]
, 1968 Anamnestic antihapten responses were obtained to trinitrophenyl (TNP) when rabbits sensitized to trinitrophenyl-hemocyanin (TNP-KLH) were challenged with TNP-heterologous protein conjugates.
Campbell, Dan H., Rittenberg, Marvin B.
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Liking, wanting, and the incentive-sensitization theory of addiction.
American Psychologist, 2016 Rewards are both "liked" and "wanted," and those 2 words seem almost interchangeable. However, the brain circuitry that mediates the psychological process of "wanting" a particular reward is dissociable from circuitry that mediates the degree to which it
K. Berridge, T. Robinson
semanticscholar +1 more source
Role of dopamine D1-like receptors in methamphetamine locomotor responses of D2 receptor knockout mice [PDF]
, 2008 Behavioral sensitization to psychostimulants manifests as an increased locomotor response with repeated administration. Dopamine systems are accepted to play a fundamental role in sensitization, but the role of specific dopamine receptor subtypes has not
Atkins +47 more
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Frontiers in Medicine, 2019 Itching can result from activity of specialized primary afferent neurons (“pruriceptors”) that have been shown to express certain molecular markers such as B-type natriuretic peptide and several members of the Mrgpr-family in rodents.
Martin Schmelz
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Prevention of common oral diseases among Senior Secondary School Students in Enugu State, Nigeria
Orapuh Journal, 2021 Introduction Oral diseases are major threats to general health but can be prevented by the adoption of healthy oral hygiene practices. Purpose This study was aimed at ascertaining the prevention of common oral diseases among selected Senior Secondary ...
Scholastica Chidi Okoli, I. A. Ogbalu
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