Results 91 to 100 of about 91,363 (358)

Tailoring the Properties of Functional Materials With N‐Oxides

open access: yesAdvanced Functional Materials, EarlyView.
The properties of materials bearing N‐oxide groups are often dominated by the polar N+─O− bond. It provides hydrophilicity, selective ion‐binding, electric conductivity, or antifouling properties. Many of the underlying mechanisms have only recently been discovered, and the interest in N‐oxide materials is rapidly growing.
Timo Friedrich   +5 more
wiley   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

A prior history of binge-drinking increases sensitivity to the motivational valence of methamphetamine in female C57BL/6J mice. [PDF]

open access: yes, 2020
Methamphetamine (MA) and alcohol use disorders exhibit a high degree of co-morbidity and sequential alcohol-MA mixing increases risk for co-abuse. Recently, we reported greater MA-conditioned reward in male C57BL/6J mice with a prior history of binge ...
Bryant, Camron D   +4 more
core   +1 more source

Electron–Matter Interactions During Electron Beam Nanopatterning

open access: yesAdvanced Functional Materials, EarlyView.
This article reviews the electron–matter interactions important to nanopatterning with electron beam lithography (EBL). Electron–matter interactions, including secondary electron generation routes, polymer radiolysis, and electron beam induced charging, are discussed.
Camila Faccini de Lima   +2 more
wiley   +1 more source

Differentiation Therapy Targeting the β-Catenin/CBP Interaction in Pancreatic Cancer. [PDF]

open access: yes, 2018
BACKGROUND:Although canonical Wnt signaling is known to promote tumorigenesis in pancreatic ductal adenocarcinoma (PDAC), a cancer driven principally by mutant K-Ras, the detailed molecular mechanisms by which the Wnt effector β-catenin regulates such ...
Chen, Yibu   +12 more
core   +2 more sources

Multipurpose Transparent Nanocomposites for Gamma Spectroscopy, Pulse Shape Discrimination, Thermal Neutron Detection, Radiation Shielding, and High Refractive Index Applications

open access: yesAdvanced Functional Materials, EarlyView.
Materials exist that are useful for gamma scintillation, radiation shielding, neutron‐gamma pulse shape discrimination (PSD), thermal neutron detection, or high refractive index applications. While certain materials have exhibited optimal performance for each of these applications, none achieve multiple functions.
Isabelle Winardi   +13 more
wiley   +1 more source

Participatory design and use of a simplified landscape in a simulation model for mitigating land use conflict in Northern Thailand highlands [PDF]

open access: yes, 2009
Landscape modelling integrating spatial information in Geographic Information Systems has been widely used to represent knowledge and support decision-making in the field of natural resource management.
Dumrongrojwatthana, P.   +3 more
core  

Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati   +2 more
wiley   +1 more source

Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells

open access: yesFrontiers in Oncology, 2012
Dendritic cells (DCs), as professional antigen presenting cells (APCs), are members of the innate immune system and function as key players during the induction phase of adaptive immune responses.
Katrin eManda   +3 more
doaj   +1 more source

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

open access: yesNature, 2014
Fibroblast growth factor 1 (FGF1) is an autocrine/paracrine regulator whose binding to heparan sulphate proteoglycans effectively precludes its circulation.
J. M. Suh   +19 more
semanticscholar   +1 more source

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