Results 121 to 130 of about 1,385,596 (346)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Differentially localizing isoforms of the migraine component calcitonin gene-related peptide (CGRP), in the mouse trigeminal ganglion: βCGRP is translated but, unlike αCGRP, not sorted into axons

The Journal of Headache and Pain
Objective The neuropeptide calcitonin gene-related peptide (CGRP) has been established to be a key signaling molecule in migraine, but little is known about the differences between the two isoforms: αCGRP and βCGRP. Previous studies have been hampered by
Sofia Lyng Wæver, Kristian Agmund Haanes   +1 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Novel nanobody-based tools for studying the synaptic vesicle life cycle [PDF]

BIO Web of Conferences
Rehm Ronja, Mougios Nikolaos, Real Karine Queiroz Zetune Villa, Sograte-Idrissi Shama, Albert László, Rahimi Amir M., Maidorn Manuel, Hentze Jannik, Martinez-Carranza Markel, Hosseini Hassan, Saal Kim-Ann, Oleksiievets Nazar, Prigge Matthias, Tsukanov Roman, Stenmark Pål, Rizzoli Silvio, Opazo Felipe, Fornasiero Eugenio   +17 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

SENSORY AND MOTOR FUNCTIONS IMPROVE LONG-TERM PREDICTIONS OF NEURODEGENERATION AND COGNITIVE DECLINE

, 2023
Natascha Merten, Adam J. Paulsen, Richard J. Chappell, Yanjun Chen, Luigi Ferrucci, Laura M. Hancock, Sterling C. Johnson, Carla R. Schubert   +7 more
openalex   +1 more source

This Is Not an Autonomous Sensory Meridian Response Video During COVID [PDF]

, 2022
Lealani Mae Y. Acosta
openalex   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

Development and validation of a large, modular test meal with liquid and solid components for assessment of gastric motor and sensory function by non‐invasive imaging

, 2016
Helen L. Parker, Emily Tucker, Caroline L. Hoad, Anabik Pal, Carolyn Costigan, Nicola Hudders, Alan C. Perkins, Elaine Blackshaw, Penny Gowland, Luca Marciani, Mark Fox   +10 more
openalex   +2 more sources

Influences of Sugar Substitutes on the Physicochemical and Sensory Properties and Hardness of Baksulgi during Storage [PDF]

, 2012
Dayeon Ryu, Dan Bi Kim, Kyung Hwan Lee, Dong Sung Son, Jeonghee Surh   +4 more
openalex   +1 more source