Results 111 to 120 of about 396,805 (256)

Human pairs show collective benefit in olfactory perception despite individual differences and verbal limits

iScience
Summary: Olfaction is a limit case for human communication. Not only does genetic, personal, and cultural diversity make us smell things differently, but perceptual and neurological factors are meant to make it challenging to verbalize our olfactory ...
Mustafa Yavuz, Saman Sayahpour, Bahador Bahrami, Ophelia Deroy   +3 more
doaj   +1 more source

Decoupling of brain function from structure reveals regional behavioral specialization in humans

, 2019
The brain is an assembly of neuronal populations interconnected by structural pathways. Brain activity is expressed on and constrained by this substrate.
Preti, Maria Giulia, Van De Ville, Dimitri   +1 more
core   +2 more sources

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Bursts of vagus nerve stimulation paired with auditory rehabilitation fail to improve speech sound perception in rats with hearing loss

iScience
Summary: Hearing loss can lead to long-lasting effects on the central nervous system, and current therapies, such as auditory training and rehabilitation, show mixed success in improving perception and speech comprehension.
Alan M. Carroll, Jonathan R. Riley, Michael S. Borland, Tanya T. Danaphongse, Seth A. Hays, Michael P. Kilgard, Crystal T. Engineer   +6 more
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Effects of corticothalamic feedback depend on visual responsiveness and stimulus type

iScience
Summary: In the dorsolateral geniculate nucleus (dLGN) of the thalamus, stimulus-driven signals combine with modulatory inputs such as corticothalamic (CT) feedback and behavioral state, but their impact in shaping dLGN activity is debated.
Lisa Schmors, Ann H. Kotkat, Yannik Bauer, Ziwei Huang, Davide Crombie, Lukas Sebastian Meyerolbersleben, Sacha Sokoloski, Philipp Berens, Laura Busse   +8 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Burst firing optimizes invariant coding of natural communication signals by electrosensory neural populations

iScience
Summary: Accurate perception of objects within the environment independent of context is essential for the survival of an organism. While neurons that respond in an invariant manner to different stimulus waveforms resulting from identitypreserving ...
Michael G. Metzen, Amin Akhshi, Pouya Bashivan, Anmar Khadra, Maurice J. Chacron   +4 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Segregated input to thalamic areas that project differently to core and shell auditory cortical fields

iScience
Summary: Perception of the environment is multimodal in nature, with sensory systems intricately interconnected. The ability to integrate multimodal sensations while preserving the distinct characteristics of each sensory modality is crucial, and the ...
Tetsufumi Ito, Mamiko Yamamoto, Li Liu, Khaleeq Ahmad Saqib, Takafumi Furuyama, Munenori Ono   +5 more
doaj   +1 more source