Results 131 to 140 of about 946,105 (288)

Vestibular sensory dysfunction: neuroscience and psychosocial behaviour overview

Social welfare : interdisciplinary approach, 2016
The objective of the submitted contribution is to describe one of the sensory dysfunction - the vestibular system. The vestibular system is crucial sensory system for other sensory systems such as tactile and proprioception, as well as having tight connection to the limbic system.
openaire   +3 more sources

Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino, Lavanya Muthukumar, Evan L. Reynolds, Peter Todd, Sinem Ovunc, Sheng Chih Jin, Zitian Tang, Simone Thomas, PNRR Study Group, Ahmet Höke, Brian C. Callaghan, Sarah Berth, Vinay Chaudhry, David Cornblath, Leana Doherty, Lindsey Hayes, Hristelina Ilieva, Thomas Lloyd, Mohammad Khoshnoodi, Brett McCray, Brett Morrison, Bipasha Mukherjee‐Clavin, Lyle Ostrow, Michael Polydefkis, Ricardo Roda, Charlotte Sumner   +25 more
wiley   +1 more source

Frontal gamma-alpha ratio reveals neural oscillatory mechanism of attention shifting in tinnitus

iScience
Summary: In clinical practice, the symptoms of tinnitus patients can be temporarily alleviated by diverting their attention away from disturbing sounds.
Xueji Feng, Xiaoyu Bao, Haiyun Huang, Zijian Wang, Wen Hu, Chenxi Xue, Zhiqing Song, Yuexin Cai, Qiyun Huang, Yuanqing Li   +9 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

A general model based on Riemannian manifold for stable decoding movement trajectory from ECoG signals

iScience
Summary: Decoding continuous 3D hand trajectories from electrocorticographic (ECoG) signals holds potential for brain-computer interface (BCI) applications. However, inter-session variability poses a major challenge for generalization.
Reza Eyvazpour, Behraz Farrokhi, Abbas Erfanian   +2 more
doaj   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Acute alcohol in prefrontal cortex is characterized by enhanced inhibition that transitions to excitation

iScience
Summary: Acute alcohol can have profound effects on the brain and behavior. Dorsal medial prefrontal cortex (dmPFC) function is especially sensitive to disruption from acute alcohol exposure.
Kathleen G. Bryant, David Swygart, Yuexi Yin, Meredith R. Bauer, Mitchell D. Morningstar, Nicholas M. Timme, William H. Barnett, Colleen E. McGonigle, Eric A. Engleman, Patrick L. Sheets, Christopher C. Lapish   +10 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Decline in Sensory Integration in Old Age and Its Related Functional Brain Connectivity Correlates Observed during a Virtual Reality Task

Sensory integration is an essential human function whose decline impacts quality of life, particularly in older adults. Herein, we propose an arm-reaching task based on a virtual reality head-mounted display system to assess sensory integration in daily ...
Ludovico Minati, Natsue Yoshimura, Satoru Inagaki, Kazuki Sakurai, Hirokazu Matsuura   +4 more
core   +1 more source

Automated sleep staging from single-channel electroencephalogram using hybrid neural network with manual features and attention

iScience
Summary: Sleep staging is essential for evaluating sleep quality, diagnosing disorders, and creating personalized treatment plans. The convolutional and bidirectional long short-term memory hybrid neural network (CNN-BiLSTM) has shown promise in ...
Qingyun Wan, Yuyang Bo, Ying Zhang, Mufeng Li, Xiaoqiu Wang, Chuang Chen, Lanying Liu, Wenzhong Wu   +7 more
doaj   +1 more source